Interrelationships between heath utility measurements, disease activity and psychological factors in Behçet's disease

The psychological impact of Behçet's disease

“…The concept is not dissimilar from the bio-psycho-social model often Case-control BD versus healthy controls Beck depression inventory (Beck et al, 1961) Visual loss in BD is associated with depression Sorgun et al (2018) Case-control Neuro BD versus non-neuro BD versus healthy controls Hamilton depression rating scale (Hamilton, 1960) Similar depression scores Murray et al (2021) Cross-sectional BD screening PHQ-9 (Levis et al, 2019) No statistically significant association with disease duration or immunomodulatory medication Yazmalar et al (2017) Case-control BD versus healthy individuals Hospital Anxiety and Depression Scale (Zigmond & Snaith, 1983) Negative association with sleep quality Gunduz et al (2012) Case-control BD versus MS Beck depression inventory (Beck et al, 1961) No statistically significant difference Saygin et al (2015) Case-control BD versus AS versus healthy controls Beck depression inventory (Beck et al, 1961) Eye, neurologic, and joint involvement appear to be important predictors of higher depression scores Saur et al (2022) Prospective cohort BD versus healthy individuals Beck depression inventory (Beck et al, 1961) Depression was prevalent in the BD group Abbreviations: AS, ankylosing spondylitis; BD, Behçet's disease; NA, not applicable; MS, multiple sclerosis; RCT, randomized controlled trial.…”

“…Depression and anxiety are significantly associated with fatigue (Ilhan et al, 2018;Murray et al, 2021).…”

“…The data regarding the association between depression and disease activity is still contradictive. While certain studies found a strong correlation between depression and greater disease activity (34; 35) or more severe disease manifestations (Gur et al., 2006; Melikoglu & Melikoglu, 2010; Saygin et al., 2015; Ucar et al., 2017), others found no significant association between depression and disease activity (Can Sandikci et al., 2019; Gunduz et al., 2012; Hayriye Sorgun et al., 2020; Murray et al., 2021; Zulfiqar et al., 2020). Depression can prolong disease duration as well (Atay et al., 2014).…”

“…In return, fatigue can worsen the quality of sleep (Tascilar et al., 2012) and functional status (Tsutsui et al., 2020). Depression and anxiety are significantly associated with fatigue (Ilhan et al., 2018; Murray et al., 2021).…”

“…All in all, the HRQoL is significantly affected in patients with BD. Disease duration (Gorial & Jabbar, 2020; Murray et al., 2021) and organ involvement (Calikoglu et al., 2001b; Ilhan et al., 2018). Seem to be major contributors to the HRQoL impact.…”