Interrelation of thermodynamic sublimation characteristics with crystal structure: adamantane and memantine derivatives of sulfonamide molecular crystals

Abstract

A number of sulfonamide compounds with adamantane (tricyclo[3.3.1.13,7]decane) and memantine (3,5-dimethyladamantan-1-amine) fragments have been synthesized and characterized.

Prediction of molecular packing characteristics of two-component crystals

“…1 In contrast, we use the β coefficient representing the free volume in a unit cell normalized to the van der Waals volume of the molecules in its content in our works. 2,3 Such normalization allows us to compare the free volumes of molecules that are different in size and topology not only for single-component but also for two-component crystals.…”