INTERRELATED VITAMIN REQUIREMENTS: KIDNEY DAMAGE, ADRENAL HEMORRHAGE AND CARDIAC FAILURE CORRELATED WITH INADEQUACY OF PANTOTHENIC ACID<sup>1</sup>

Supplee, G.C.; Bender, R. C.; Kahlenbergd, O. J.; Babcock, L.C.

doi:10.1210/endo-30-3-355

Cited by 25 publications

(4 citation statements)

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“…These rations were also well fortified with vitamin B12 and contained 2 units percent more protein. This would seem to confirm the probable variation in pantothenic acid requirements depending on age, weight, condition and ration as suggested by Supplee (1942). It was also thought that the added vitamin B12 might have a sparing effect on pantothenic acid in pigs as reported by Yacowitz et al (1950) in chicks.…”

Section: Experiments Isupporting

confidence: 75%

Effects of Certain Antibiotics and Vitamin B12 on Pantothenic Acid Requirements of Growing-Fattening Swine1

Catron¹,

Bennison²,

Maddock³

et al. 1953

Journal of Animal Science

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S UPPLEE et al. (1942) showed that the pantothenic acid requirements of the pig depend on several factors, including stage of development, previous nutritional history and interrelationships with other nutrients. Rations of natural feedstuffs were found by McMillen et al. (1948) to be low or borderline in pantothenic acid for maximum growth of pigs. Luecke et al. (1949 and 1950) produced characteristic pantothenic acid deficiencies with both semi-synthetic and natural rations containing 3.4, 3.8 and 4.2 mg. of pantothenic acid per pound of ration in the absence of added vitamin BI.-and antibiotics. Vohs et al. (1950) found that 5 mcg. vitamin B12 per pound of cornsoybean oil meal ration were adequate for optimum growth in growingfattening swine. Using crystalline vitamin B t2, Richardson et al. (1951) reported the vitamin Ble requirements of young growing pigs to be 5 mcg. or less in the presence of antibiotics (40 mg. per pound of ration). They observed an interaction between antibiotics and vitamin BI.-. Yacowitz et al. (1950), working with chicks, found that vitamin B12 and pantothenic acid spared each other. Evans et al. (1951) found that in the absence of sufficient vitamin B12, pantothenic acid accumulates in the liver; indicating that vitamin B~e aids in the transfer of pantothenic acid from the liver for use elsewhere in the chick's body. Antibiotics have been found to increase rate of gain by various workers including Lepley et al. (1950), Catron et al. (1951), Speer et al. (1951) and Luecke et al. (1951). Swick et al. (1951) showed aureomycin and streptomycin to be superior to other antibiotics for increasing growth in pantothenic acid deficient rats.

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Section: Experiments Isupporting

confidence: 75%

Effects of Certain Antibiotics and Vitamin B12 on Pantothenic Acid Requirements of Growing-Fattening Swine1

Catron¹,

Bennison²,

Maddock³

et al. 1953

Journal of Animal Science

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“…Table 1 shows the decrease in body and liver weight. The adrenal glands were relatively enlarged and often haemorrhagic, as reported by Supplee, Bender & Kahlenberg (1942) and by Deane & McKibbin (1946).…”

Section: Resultsmentioning

confidence: 51%

Liver lipids and ketone-body formation in rats deficient in pantothenate

Carter¹,

Hockaday²

1962

Biochemical Journal

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“…1): and some, by definition, still confine it to this disease. The syndrome has been found in other infectious diseases such as diphtheria (Maclean, 1937) and influenza (Lucke, Wight and Kime, 1919) and in such diverse conditions as toxaemia of pregnancy (Dodds, 1945), dietary deficiency (Supplee, Bender and Kahlenberg, 1942), pneumonia, scarlet fever, dysentery, typhoid and malaria and in the puerperium (Dewhurst, 1951).…”

Section: Figmentioning

confidence: 99%

Waterhouse Friderichsen Syndrome

Emery

1953

Int J Clinical Practice

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INTERRELATED VITAMIN REQUIREMENTS: KIDNEY DAMAGE, ADRENAL HEMORRHAGE AND CARDIAC FAILURE CORRELATED WITH INADEQUACY OF PANTOTHENIC ACID¹

Cited by 25 publications

References 0 publications

Effects of Certain Antibiotics and Vitamin B12 on Pantothenic Acid Requirements of Growing-Fattening Swine1

Effects of Certain Antibiotics and Vitamin B12 on Pantothenic Acid Requirements of Growing-Fattening Swine1

Liver lipids and ketone-body formation in rats deficient in pantothenate

Waterhouse Friderichsen Syndrome

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INTERRELATED VITAMIN REQUIREMENTS: KIDNEY DAMAGE, ADRENAL HEMORRHAGE AND CARDIAC FAILURE CORRELATED WITH INADEQUACY OF PANTOTHENIC ACID1

Cited by 25 publications

References 0 publications

Effects of Certain Antibiotics and Vitamin B12 on Pantothenic Acid Requirements of Growing-Fattening Swine1

Effects of Certain Antibiotics and Vitamin B12 on Pantothenic Acid Requirements of Growing-Fattening Swine1

Liver lipids and ketone-body formation in rats deficient in pantothenate

Waterhouse Friderichsen Syndrome

Contact Info

Product

Resources

About

INTERRELATED VITAMIN REQUIREMENTS: KIDNEY DAMAGE, ADRENAL HEMORRHAGE AND CARDIAC FAILURE CORRELATED WITH INADEQUACY OF PANTOTHENIC ACID¹