Interpreting the molecular mechanisms of RBBP4/7 and their roles in human diseases (Review)
Yajing Zhan,
Ankang Yin,
Xiyang Su
et al.
Abstract:Histone chaperones serve a pivotal role in maintaining human physiological processes. They interact with histones in a stable manner, ensuring the accurate and efficient execution of DNA replication, repair and transcription. Retinoblastoma binding protein (RBBP)4 and RBBP7 represent a crucial pair of histone chaperones, which not only govern the molecular behavior of histones H3 and H4, but also participate in the functions of several protein complexes, such as polycomb repressive complex 2 and nucleosome rem… Show more
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