Interpreting myocardial perfusion scintigraphy using single-photon emission computed tomography. Part 1

Czaja, Monika; Wygoda, Zbigniew; Duszańska, Agata; Szczerba, Dominik; Głowacki, Jan; Gąsior, Mariusz; Wasilewski, Jarosław

doi:10.5114/kitp.2017.70534

Cited by 29 publications

(32 citation statements)

References 15 publications

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“…Gated data used for quantitative results including end systolic volume, end diastolic volume, and ejection fraction of left ventricle. Stress-induced transient ischemic dilatation was also identified [6].…”

Section: Imaging Interpretationmentioning

confidence: 95%

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The value of myocardial MIBI washout rate in risk stratification of coronary artery disease

Othman

Moustafa

El-Ghany

et al. 2021

Egypt J Radiol Nucl Med

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Background Although it is well established that MIBI does not redistribute as thallium within the myocardium, it showed a reverse redistribution phenomenon that can be expressed by the rate of myocardial MIBI washout. The aim in this study was calculating the global myocardial washout of the MIBI (GWR) in patients diagnosed with coronary artery disease (CAD) of different risk stratifications. Results This prospective study included 100 patients. All patients were stratified into low-, intermediate-, and high-risk groups according to clinical evaluation using Framingham score, stress ECG results using Duke’s score and finally myocardial perfusion imaging prognostic findings. GWR was estimated in each of these groups. GWR mean was 9.5%, 13%, and 18% within clinically stratified patients into low-, intermediate-, and high-risk patients respectively with correlation coefficient 0.4. In addition, GWR mean was 9.7%, 15.4%, and 18.7% within patients stratified according to exercise ECG findings into low-, intermediate-, and high-risk patients respectively with correlation coefficient 0.6. Combining all myocardial perfusion findings, GWR mean was 7.9%, 15.1%, and 19.3% in patient with low-, intermediate-, and high-risk imaging findings respectively with correlation coefficient 0.71. Conclusion GWR is positively correlated with the risk stratifications of the CAD patients. GWR can be used as an additional parameter to assess the risk of CAD patients.

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Section: Imaging Interpretationmentioning

confidence: 95%

“…A summed rest score (SRS) and summed stress score (SSS) were obtained by adding the scores of the 17 segments of the rest and stress images, respectively. The summed difference score (SDS) was determined by subtracting the SRS from the SSS [6].…”

Section: Imaging Interpretationmentioning

confidence: 99%

The value of myocardial MIBI washout rate in risk stratification of coronary artery disease

Othman

Moustafa

El-Ghany

et al. 2021

Egypt J Radiol Nucl Med

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“…For SSS and SRS, the higher the score, the greater the extent of ischemia. Transient ischemic dilatation is a measure of left ventricular cavity volume at stress and rest, and the greater the volume at stress in relation to rest, there is a correlation with multivessel coronary disease [25].…”

Section: Methodsmentioning

confidence: 99%

Lung Sestamibi Uptake on Myocardial Perfusion Imaging and Outcomes in Chronic Kidney Disease

et al. 2021

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Background and Objectives: In patients with CKD and end-stage kidney disease (ESKD), cardiac stress testing has low sensitivity and specificity for coronary disease. Alternate markers that are derived during the stress testing may enhance the predictive characteristic of stress testing. The objective was to examine the predictive characteristic of lung-to-heart ratio (LHR) in patients with CKD and ESKD. Design, Setting, Participants, and Measurements: Retrospective parallel cohort of ESKD and CKD not on dialysis (CKD-ND) who underwent stress testing with nuclear myocardial perfusion imaging utilizing sestamibi tracer and regadenoson. Stress LHR was calculated by the processing software and reported. Patients were analyzed by tertile of LHR (≤0.28, 0.29–0.32, ≥0.33). The primary outcome was a composite of all-cause mortality, hospitalization for myocardial infarction or unstable angina, or revascularization. Results: There were 144 CKD-ND and 145 ESKD patients. Patients with ESKD had greater comorbidity burden than CKD-ND. Stress tests were more often performed for pre-operative risk assessment among ESKD versus CKD-ND (53.8 vs. 5.6%, p < 0.001). ESKD patients more likely had ischemia identified on stress testing (19.3 vs. 8.3%, p = 0.001). Mean LHR was 0.31 (Standard deviation – SD: 0.09) and was similar across CKD-ND stages and ESKD. Primary outcome in the lowest (23%) and highest (33.3%) LHR tertile was higher than the middle tertile (12.8%); p = 0.005. This finding was similar between CKD-ND and ESKD and persisted in multivariable analysis. Conclusions: LHR ≤0.28 and ≥0.33 are independently associated with higher risk for death in patients with CKD-ND and ESKD. Future studies are warranted to understand the association of extreme LHR values and outcomes in this high-risk population.

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“…The cardiac apex exhibits higher motion in comparison to the basal segments, among which the anterolateral and inferolateral segments (segments 6 and 5, respectively) are characterized by higher motion when compared to the anteroseptal and inferoseptal segments (segments 2 and 3, respectively). The division of the polar map into segments was shown in Figure 2 in the first part of this review [ 1 ].…”

Section: Evaluation Of Regional Left Ventricular Contractility In Gatmentioning

confidence: 99%

Myocardial perfusion scintigraphy – interpretation of gated imaging. Part 2

Czaja

Wygoda²,

Duszańska

et al. 2018

kitp

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The first part of the review describes the basic aspects of interpreting myocardial perfusion defects in single photon emission computed tomography (SPECT) scintigraphy. It also presents indications for invasive diagnostics based on stress perfusion defects. This article provides basic information concerning the interpretation of gated SPECT imaging, including such parameters as left ventricular wall motion and thickening as well as left ventricular wall systolic and diastolic function. Gated examination combined with the assessment of myocardial perfusion reduces the rate of false positives results of myocardial perfusion scintigraphy in perfusion tests, additionally providing data on left ventricular systolic and diastolic function.

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Interpreting myocardial perfusion scintigraphy using single-photon emission computed tomography. Part 1

Cited by 29 publications

References 15 publications

The value of myocardial MIBI washout rate in risk stratification of coronary artery disease

The value of myocardial MIBI washout rate in risk stratification of coronary artery disease

Lung Sestamibi Uptake on Myocardial Perfusion Imaging and Outcomes in Chronic Kidney Disease

Myocardial perfusion scintigraphy – interpretation of gated imaging. Part 2

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