Interpretation of the Visual Field in Neuro-ophthalmic Disorders

Banc, Ana; Kedar, Sachin

doi:10.1007/s11910-024-01332-3

Cited by 1 publication

(1 citation statement)

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“…The patterns of VFDs provide important clues for the precise localization of the lesions of the afferent visual pathway. Unilateral prechiasmal lesions typically manifest as nerve fiber bundle-type patterns, whereas chiasmal and retrochiasmal disorders commonly result in bilateral VFDs with respect to the vertical meridian [ 14 , 16 ]. Understanding these patterns is essential to revealing the underlying disorder and adjusting interventions accordingly.…”

Section: Introductionmentioning

confidence: 99%

Macular OCT’s Proficiency in Identifying Retrochiasmal Visual Pathway Lesions in Multiple Sclerosis—A Pilot Study

Cujbă,

Banc,

Stan

et al. 2024

Diagnostics

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Optical coherence tomography (OCT) is a non-invasive imaging technique based on the principle of low-coherence interferometry that captures detailed images of ocular structures. Multiple sclerosis (MS) is a neurodegenerative disease that can lead to damage of the optic nerve and retina, which can be depicted by OCT. The purpose of this pilot study is to determine whether macular OCT can be used as a biomarker in the detection of retrochiasmal lesions of the visual pathway in MS patients. We conducted a prospective study in which we included 52 MS patients and 27 healthy controls. All participants underwent brain MRI, visual field testing, and OCT evaluation of the thicknesses of the peripapillary retinal nerve fiber layer (pRNFL), macular ganglion cell layer (GCL), and macular inner plexiform layer (IPL). OCT measurements were adjusted for optic neuritis (ON). VF demonstrated poor capability to depict a retrochiasmal lesion identified by brain MRI (PPV 0.50). In conclusion, the OCT analysis of the macula appears to excel in identifying retrochiasmal MS lesions compared to VF changes. The alterations in the GCL and IPL demonstrate the most accurate detection of retrochiasmal visual pathway changes in MS patients.

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Section: Introductionmentioning

confidence: 99%