Interpretation of laboratory results: the Reference Intervals, a necessary evil?

Henny, Joseph

doi:10.1515/cclm.2007.272

Cited by 6 publications

(1 citation statement)

References 3 publications

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“…Ook methoden zoals 99%-referentiewaarden, 'critical differences' en een computer-expertsysteem (Valab) 13 bleken geen van alle voldoende in staat om alle afkappunten objectief te bepalen. 20 Een mogelijkheid is het gebruik van 'decision limits' die aangeven wanneer een bepaalde uitslag een klinische consequentie heeft. Het laboratoriumonderzoek heeft dan meestal weinig toegevoegde waarde, en er zijn dan ook meerdere manieren onderzocht om zulke overbodige diagnostiek terug te dringen.…”

Section: Wat Is Nieuw?unclassified

Redenen om laboratoriumdiagnostiek aan te vragen en interpretatie van de uitslagen

Houben¹,

Weijden²,

Winkens³

et al. 2010

HUWE

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Mogelijke belangenverstrengeling: niets aangegeven. Dit artikel is een samenvatting van twee artikelen, gepubliceerd als: Houben PH, Van der Weijden T, Winkens B, Winkens RA, Grol RP. Pretest expectations strongly influence interpretation of abnormal laboratory results and further management. BMC Fam Pract 2010;11:13; Houben PH, Winkens RA, Van der Weijden T, Vossen RC, Naus AJ, Grol RP. Reasons for ordering laboratory tests and relationship with frequency of abnormal results. Scand J Prim Health Care 2010;28:18-23. Publicatie gebeurt met toestemming van de uitgevers.

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Section: Wat Is Nieuw?unclassified

Redenen om laboratoriumdiagnostiek aan te vragen en interpretatie van de uitslagen

Houben¹,

Weijden²,

Winkens³

et al. 2010

HUWE

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Study of the endogenous steroid profile of male athletes from the Brazilian National Soccer Championship 2009

Nicolich

Padilha

Neto

2010

Drug Testing and Analysis

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Changes in the endogenous profile of androgenic anabolic steroids (AAS) may be interpreted as markers of doping. The objective of this study was to evaluate the endogenous profile of AAS in male athletes of the 2009 Brazilian National Soccer Championship, in normal conditions, particularly in the light of the revision of World Anti-Doping Agency's (WADA) Technical Document on the Interpretation of Endogenous AAS in athletes for doping control drafted in that year, as well as comparing these results to profiles already published in the literature. The upper limit of the 95% central reference interval of the following parameters for the studied population were estimated to be significantly higher than WADA's criteria, with a confidence of 90%: DHEA (about 2.3 times higher), Adiol (1.2 times higher), Bdiol (2.7 times higher), and Adiol/E (6 times higher). These findings seem to imply that WADA's criteria proposed in 2009 for DHEA, Adiol, Bdiol, and Adiol/E may not have been applicable to the studied population. Moreover, their comparison to previously published studies pointed to the need to evaluate in detail the appropriateness of adopting these criteria as universal, since there seems to be variations among different populations of athletes.

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The comparison of parametric and nonparametric bootstrap methods for reference interval computation in small sample size groups

et al. 2012

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Interpretation of laboratory results: the Reference Intervals, a necessary evil?

Cited by 6 publications

References 3 publications

Redenen om laboratoriumdiagnostiek aan te vragen en interpretatie van de uitslagen

Redenen om laboratoriumdiagnostiek aan te vragen en interpretatie van de uitslagen

Study of the endogenous steroid profile of male athletes from the Brazilian National Soccer Championship 2009

The comparison of parametric and nonparametric bootstrap methods for reference interval computation in small sample size groups

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