Interpretation of In Vitro Concentration-Response Data for Risk Assessment and Regulatory Decision-making: Report from 2022 IWGT Quantitative Analysis Expert Working Group Meeting
Abstract:Quantitative risk assessments of chemicals are routinely performed in
rodents; however, there is growing recognition that non-animal
approaches can be human-relevant alternatives. There is an urgent need
to build confidence in non-animal alternatives given the international
support to reduce the use of animals in toxicity testing where possible.
In order for scientists and risk assessors to prepare for this paradigm
shift in toxicity assessment, standardization and consensus on in vitro
testing strategies and … Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.