Abstract:Correlation among species, sex, and tumor-site of neoplastic responses in 25 chemicals tested for carcinogenicity at the An-Pyo Center in 1981-1993 were evaluated. Of the 25 chemicals tested in rats and mice, 44 percent (1l of 25) were positive in at least one species and 56 percent (14 of 25) were negative in both rats and mice. Rats and mice exhibited a similar sensitivity to carcinogens as evidenced by 8 positive studies in rats and 9 positive studies in mice for a total of 17 positive studies. Three of the… Show more
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.