Interpretation of automated blood cell counts

Kaya, Zühre

doi:10.5798/diclemedj.0921.2013.03.0326

Cited by 12 publications

(10 citation statements)

References 26 publications

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“…In our study, the WBC value was over 17,000 / µL between 0-2 years old, over 15,000 / µL between 2-4 years old, over 14,000 / µL between 4-6 years old and over 13,000 / µL between 6-18 years old accepted as leukocytosis [12]. In cases where one or more symptoms of temporary loss of consciousness, vomiting, headache, dizziness at the time of the event, it is accepted that there is symptoms.…”

Section: Methodssupporting

confidence: 48%

Prognostic Value Of Leukocytosis In Pediatric Head Trauma

Şahin

Kayabaş

Aras

2020

Preprint

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Purpose Our aim in this study is to investigate the relationship between age, gender, trauma etiology, presence of symptoms at the time of admission, Glasgow Coma Scale (GCS), brain CT findings and blood WBC levels at admission. Methods 305 pediatric patients [between 0 and 18 years old] who applied to the emergency department of Kafkas University Medical Faculty Hospital between 2016 and 2019 after head trauma were included in the study. The data of these patients were analyzed retrospectively from the hospital records. Age, gender, head trauma etiology, GCS scores at the time of presentation, their symptoms, their brain CT findings and blood WBC levels were examined. Chi-square test was performed between patients with and without leukocytosis and independent variables. Results After applying exclusion factors, the data of 173 patients who underwent CT in the emergency room after head trauma and whose blood tests were studied were examined. When patients were analyzed according to gender, 111 (64.2%) were male and 62 (35.8%) were found to be female. In terms of age, it was seen that those between the ages of 0 and 2 were 54 (31.2%), and those between the ages of 2- and 18 were 119 (68.8%). Among the etiological causes of traumas, the most frequent (n = 113) 65.3% falls were seen. The number of patients with symptoms was 57 (32.9%). Patients with GCS 14 ≥ constituted 69.4% of the total patients (n = 120). There was a pathological finding in 19.0% of the brain CT' s (n = 33) taken. Leukocytosis was detected in 17.3% of the patients [n = 30]. Conclusion As a result of this study, it was found statistically significant that the blood WBC levels were higher in children who had head trauma, whose GCS was 13 ≤ at the time of application, who had symptoms and who had pathology in brain CT compared to other groups.

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Section: Methodssupporting

confidence: 48%

Prognostic Value Of Leukocytosis In Pediatric Head Trauma

Şahin

Kayabaş

Aras

2020

Preprint

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“…The strict control of pre-analytical factors might explain our higher red cell reference intervals compared with some of those studies. The likeliest explanation might be the stringency of the inclusion criteria that avoided the conditions known to influence counts [19]. The finding of higher values for hemoglobin, hematocrit and erythrocytes in males compared to females may be partly due to the influence of androgen on erythropoiesis.…”

Section: Resultsmentioning

confidence: 99%

The largest reference range study for hematological parameters from Turkey: A case control study

Tekkeşin

Beköz²,

Tükenmez³

2014

J Clin Exp Invest

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Objective: Accurate, reliable laboratory reference ranges are essential for effective clinical evaluation and monitoring. We present robust reference ranges established for hematology parameters using the Sysmex XT2000i analyzer.Methods: Blood samples were taken from 17409 healthy adults (19 to 49 years, 51.4% men and 48.6% women) and routine hematology analysis performed. Patients were assessed as healthy on the basis of a medical history and routine medical examinations. Serum hematinic assays (vitamin B12, folate, iron and ferritin) were also analyzed in order to exclude the potential anemia existence.Results: There was a statistically significant difference (p<0.001) between men and women, with the former showing higher CBC values, except WBC, neutrophil and platelet counts compared to females. Several differences were observed when compared to previously established values from Turkey, most notably in leucocytes and platelets. Our findings for CBC parameters, except leucocyte count and MCV are in general agreement with previously published data from more limited trials undertaken in other countries. Conclusions:In spite of the uncontrolled factors influencing hematological values, this study permitted to establish the new hematological reference values in Turkey, especially living near sea level. In the absence of previously detailed investigated hematological reference values in Turkey, we offered to use these results for clinical management of Turkish patients and interpretations of laboratory data for research purpose. J Clin Exp Invest 2014; 5 (4): 548-552

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“…With the activation of the systemic response after trauma, the inflammatory process begins. In the evaluation of trauma patients, parameters such as acute phase reactants, cytokines and lactate levels related to the systemic response of the organism are used (21). Inflated WBC values are generally considered to be non-specific indicators of infection, inflammation, tissue necrosis, bleeding, or stressful situations.…”

Section: Discussionmentioning

confidence: 99%

Prognostic Value of Leukocytosis in Pediatric Head Trauma

Şahin¹,

Kayabaş²,

Aras³

2020

jmbas

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Introduction: The most common cause of the morbidity and mortality in the childhood period age group is head traumas. In emergency departments computed tomography (CT) for diagnostic purposes is used more frequently in head traumas that are occurred in pediatric patients than in adults. Different protocols have been defined for brain CT in children with head trauma, clinical evaluations come to the fore in these protocols; however, there is no biomarker. Objective: Our aim in this study is to investigate the relationship between age, gender, trauma etiology, presence of symptoms at the time of admission, Glasgow Coma Scale (GCS), brain CT findings and blood WBC levels at admission. Method: 305 pediatric patients [between 0 and 18 years old] who applied to the emergency department of Kafkas University Medical Faculty Hospital between 2016 and 2019 after head trauma were included in the study. The data of these patients were analyzed retrospectively from the hospital records. Age, gender, head trauma etiology, GCS scores at the time of presentation, their symptoms, their brain CT findings and blood WBC levels were examined. Chi-square test was performed between patients with and without leukocytosis and independent variables. Results: After applying exclusion factors, the data of 173 patients who underwent CT in the emergency room after head trauma and whose blood tests were studied were examined. When patients were analyzed according to gender, 111 (64.2%) were male and 62 (35.8%) were found to be female. In terms of age, it was seen that those between the ages of 0 and 2 were 54 (31.2%), and those between the ages of 2- and 18 were 119 (68.8%). Among the etiological causes of traumas, the most frequent (n = 113) 65.3% falls were seen. The number of patients with symptoms was 57 (32.9%). Patients with GCS 14 ≥ constituted 69.4% of the total patients (n = 120). There was a pathological finding in 19.0% of the brain CT' s (n = 33) taken. Leukocytosis was detected in 17.3% of the patients [n = 30]. Conclusion: As a result of this study, it was found statistically significant that the blood WBC levels were higher in children who had head trauma, whose GCS was 13 ≤ at the time of application, who had symptoms and who had pathology in brain CT compared to other groups.

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Interpretation of automated blood cell counts

Cited by 12 publications

References 26 publications

Prognostic Value Of Leukocytosis In Pediatric Head Trauma

Prognostic Value Of Leukocytosis In Pediatric Head Trauma

The largest reference range study for hematological parameters from Turkey: A case control study

Prognostic Value of Leukocytosis in Pediatric Head Trauma

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