This chapter presents a design scheme to generate tight and so-called semi-tight frames in the space of discrete-time periodic signals. The frames originate from three-and four-channel perfect reconstruction periodic filter banks. The filter banks are derived from interpolating and quasi-interpolating polynomial splines and from discrete splines. Each filter bank comprises one linear phase low-pass filter (in most cases interpolating) and one high-pass filter, whose magnitude's response mirrors that of a low-pass filter. In addition, these filter banks comprise one or two band-pass filters. In the semi-tight frames case, all the filters have linear phase and (anti)symmetric impulse response, while in the tight frame case, some of band-pass filters are slightly asymmetric. The design scheme enables to design framelets with any number of LDVMs.The computational complexity of the framelet transforms practically does not depend on the number of LDVMs and on the size of the impulse response of filters. Recently frames or redundant expansions of signals have attracted considerable interest from researchers working in signal processing although one particular class of frames, the Gabor systems, has been applied and investigated since 1946 [11]. As the requirement of one-to-one correspondence between the signal and its transform coefficients is dropped, there is more freedom to design and implement frame transforms. Frame expansions of signals demonstrate resilience to quantization noise and to coefficients losses [12][13][14]. Thus, frames may serve as a tool for error correction of signals that are transmitted through lossy/noisy channels. Recently, overcomplete representation of signals was applied to image reconstruction [5,6]. Combination of wavelet frames with the Bregman iterations techniques [2,19] provided a new impact to the image processing applications such as deconvolution, inpainting, denoising, to name a few [3,4,9,17,18]. It was mentioned in Sect. 2.2 that oversampled PR filter banks generate a specific kind of frames in the periodic signal space. This chapter presents families of frames whose generating three-and four-channel p-filter banks originate from polynomial and discrete splines. These frames have properties such as symmetry, interpolation, and flat spectra, which are attractive for signal processing.