Abstract:SummaryInterpleural blockade is effective in treating unilateral surgical and non-surgical pain from the chest and upper abdomen in both the acute and chronic settings. It has been shown to provide safe, highquality analgesia after cholecystectomy, thoracotomy, renal and breast surgery, and for certain invasive radiological procedures of the renal and hepatobiliary systems. It has also been used successfully in the treatment of pain from multiple rib fractures, herpes zoster, complex regional pain syndromes, t… Show more
“…Local anesthetic is deposited between the parietal and visceral pleura [158][159][160], where it then diffuses to the subpleural space and the intercostal nerves [159][160][161]. In one RCT comparing single-injection interpleural and single-level paravertebral blocks (both bupivacaine 0.5%) for patients undergoing mastectomy, pain scores and analgesic consumption were similar for both interventions [161].…”
Section: Interpleural Blocksmentioning
confidence: 99%
“…Both treatment groups also exhibited decreased lung functions on the first postoperative day, which improved to near-normal levels by the second postoperative day. Risks of this procedure include pneumothorax, intravascular injection, and intra-bronchial infection [159,160]. Similar to the Pecs blocks, there is extremely little data involving interpleural blocks on which to base recommendations regarding breast surgery anesthesia and analgesia.…”
Objective. To review the published evidence regarding perioperative analgesic techniques for breast cancer-related surgery.Design. Topical review.Methods. Randomized, controlled trials (RCTs) were selected for inclusion in the review. Also included were large prospective series providing estimates of potential risks and technical reports and small case series demonstrating a new technique or approaches of interest to clinicians.Results. A total of 514 abstracts were reviewed, with 284 studies meeting criteria for full review. The evidence regarding preemptive ketamine, scheduled opioids, perioperative non-steroidal anti-inflammatory drugs (NSAIDs), and intravenous lidocaine is mixed and deserves further investigation. There is strong evidence that both pregabalin and gabapentin provide analgesic benefits following breast surgery. There is minimal and conflicting data from highquality randomized, controlled studies suggesting that directly infiltrating and/or infusing local anesthetic (liposome encapsulated or unencapsulated) into the surgical wound is a reliably effective analgesic. In contrast, there is a plethora of data demonstrating the potent analgesia, opioid sparing, and decreased opioid-related side effects from thoracic epidural infusion and both single-injection and continuous paravertebral nerve blocks (the latter two demonstrating decreased persistent post-surgical pain between 2.5 and 12 months). Techniques with limited-yet promising-data deserving additional investigation include brachial plexus blocks, cervical epidural infusion, interfascial plane blocks, and interpleural blocks.Conclusions. While there are currently multiple promising analgesic techniques for surgical procedures of the breast that deserve further study, the only modalities demonstrated to provide potent, consistent perioperative pain control are thoracic epidural infusion and paravertebral nerve blocks.
“…Local anesthetic is deposited between the parietal and visceral pleura [158][159][160], where it then diffuses to the subpleural space and the intercostal nerves [159][160][161]. In one RCT comparing single-injection interpleural and single-level paravertebral blocks (both bupivacaine 0.5%) for patients undergoing mastectomy, pain scores and analgesic consumption were similar for both interventions [161].…”
Section: Interpleural Blocksmentioning
confidence: 99%
“…Both treatment groups also exhibited decreased lung functions on the first postoperative day, which improved to near-normal levels by the second postoperative day. Risks of this procedure include pneumothorax, intravascular injection, and intra-bronchial infection [159,160]. Similar to the Pecs blocks, there is extremely little data involving interpleural blocks on which to base recommendations regarding breast surgery anesthesia and analgesia.…”
Objective. To review the published evidence regarding perioperative analgesic techniques for breast cancer-related surgery.Design. Topical review.Methods. Randomized, controlled trials (RCTs) were selected for inclusion in the review. Also included were large prospective series providing estimates of potential risks and technical reports and small case series demonstrating a new technique or approaches of interest to clinicians.Results. A total of 514 abstracts were reviewed, with 284 studies meeting criteria for full review. The evidence regarding preemptive ketamine, scheduled opioids, perioperative non-steroidal anti-inflammatory drugs (NSAIDs), and intravenous lidocaine is mixed and deserves further investigation. There is strong evidence that both pregabalin and gabapentin provide analgesic benefits following breast surgery. There is minimal and conflicting data from highquality randomized, controlled studies suggesting that directly infiltrating and/or infusing local anesthetic (liposome encapsulated or unencapsulated) into the surgical wound is a reliably effective analgesic. In contrast, there is a plethora of data demonstrating the potent analgesia, opioid sparing, and decreased opioid-related side effects from thoracic epidural infusion and both single-injection and continuous paravertebral nerve blocks (the latter two demonstrating decreased persistent post-surgical pain between 2.5 and 12 months). Techniques with limited-yet promising-data deserving additional investigation include brachial plexus blocks, cervical epidural infusion, interfascial plane blocks, and interpleural blocks.Conclusions. While there are currently multiple promising analgesic techniques for surgical procedures of the breast that deserve further study, the only modalities demonstrated to provide potent, consistent perioperative pain control are thoracic epidural infusion and paravertebral nerve blocks.
“…14) Pneumothorax may occur because of air entrainment or as a result of damage to the lung parenchyma caused by the percutaneous technique of catheter placement. 15) Placement under direct vision such as our technique clearly reduces the incidence of pneumothorax.…”
Purpose: to evaluate the efficacy and safety of intrapleural analgesia (IPA) using ropivacaine after thoracoscopic surgery, compared with thoracic epidural analgesia (TEA) using ropivacaine. Methods: forty patients undergoing thoracoscopic bullectomy for spontaneous pneumothorax were randomly assigned to one of two groups. IPA group (n = 20) received intermittent bolus injection of 0.375% ropivacaine into intrapleural space two times; at the end of operation and one more time as the pain increased. TEA group (n = 20) received continuous epidural analgesia with 0.375% ropivacaine. Transrectal diclofenac was administered as an additional analgesic. Pain was assessed on the basis of additional analgesics requirements and by using a visual analog scale (VAS). Results: the time courses of VAS scores along the postoperative time course were not significantly different (p = 0.175). Consumption of transrectal diclofenac was significantly smaller in IPA group (p = 0.025). No major complications appeared in both groups, and incidence of adverse symptoms was not different. Conclusions: in IPA group, pain was managed with less consumption of additional analgesics. IPA could be one of the good choices after thoracoscopic surgery for its efficacy, safety, and benefit of easy placement of the catheter.
“…We thank Drs Al-Naimi, Hussain and Pennefather for their interest in our article [1,2] and are grateful for their comments. Their experience [3] reinforces the limitations discussed in our review that this block would be of no benefit where the pleural cavity has blood, exudates or air.…”
Section: A Replymentioning
confidence: 99%
“…It would be interesting to see if an interpleural catheter kept in the upper pleural cavity at the end of surgery, or a period of Trendelenberg positioning after administering the local anaesthetic could be usefully utilised for controlling shoulder pain. We read with interest the recent review articles concerning interpleural blocks [1,2]. In particular we noted the suggestion that interpleural blocks may have an important role for patients with clotting abnormalities.…”
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