2024
DOI: 10.1101/2024.03.10.584287
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Interplay of actin nematodynamics and anisotropic tension controls endothelial mechanics

Claire A. Dessalles,
Nicolas Cuny,
Arthur Boutillon
et al.

Abstract: Blood vessels expand and contract actively, while continuously experiencing dynamic external stresses from the blood flow. The mechanical response of the vessel wall is that of a composite material: its mechanical properties depend on a diverse set of cellular mechanical components, which change dynamically as cells respond to external stress. Mapping the relationship between these underlying cellular processes and emergent tissue mechanics is an on-going challenge, in particular in endothelial cells. Here we … Show more

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