Interplay between mesenchymal stem cells and macrophages: Promoting bone tissue repair
Fei-Fan Zhang,
Yang Hao,
Kuai-Xiang Zhang
et al.
Abstract:The repair of bone tissue damage is a complex process that is well-orchestrated in time and space, a focus and difficulty in orthopedic treatment. In recent years, the success of mesenchymal stem cells (MSCs)-mediated bone repair in clinical trials of large-area bone defects and bone necrosis has made it a candidate in bone tissue repair engineering and regenerative medicine. MSCs are closely related to macrophages. On one hand, MSCs regulate the immune regulatory function by influencing macrophages proliferat… Show more
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