Interplay between membrane proteins and membrane protein‐lipid pertaining to plant salinity stress

Abstract

High salinity in agricultural lands is one of the predominant issues limiting agricultural yields. Plants have developed several mechanisms to withstand salinity stress, but the mechanisms are not effective enough for most crops to prevent and persist the salinity stress. Plant salt tolerance pathways involve membrane proteins that have a crucial role in sensing and mitigating salinity stress. Due to a strategic location interfacing two distinct cellular environments, membrane proteins can be considered checkpoints to the salt tolerance pathways in plants. Related membrane proteins functions include ion homeostasis, osmosensing or ion sensing, signal transduction, redox homeostasis, and small molecule transport. Therefore, modulating plant membrane proteins' function, expression, and distribution can improve plant salt tolerance. This review discusses the membrane protein–protein and protein–lipid interactions related to plant salinity stress. It will also highlight the finding of membrane protein–lipid interactions from the context of recent structural evidence. Finally, the importance of membrane protein–protein and protein–lipid interaction is discussed, and a future perspective on studying the membrane protein–protein and protein–lipid interactions to develop strategies for improving salinity tolerance is proposed.

Structural and Molecular Dynamic Simulation Studies of CBL-Interacting Protein Kinase CIPK and its Complexes Related to Plant Salinity Stress

“…Simulation data suggesting a steady shift of the active site loop towards the PPI domain and the 20 GTFA 23 manifests the autoinhibition mechanism. Membrane transporters and protein-lipid interaction in membrane is suggested to be one of the pivotal phenomena during salinity stress in plants [3,13]. CIPKs activating ions transporting membrane proteins must be membrane proximal phenomena.…”