Interplay between cognition and weight reduction in individuals following a Mediterranean Diet: Three-year follow-up of the PREDIMED-Plus trial

Soldevila‐Domenech, Natalia; Forcano, Laura; Vintró-Alcáraz, Cristina; Cuenca‐Royo, Aida; Pintó, Xavier; Jiménez‐Murcia, Susana; García‐Gavilán, Jesús; Nishi, Stephanie K.; Babió, Nancy; Gomis-González, María; Corella, Dolores; Sorlí, José V.; Fernández-Carrión, Rebeca; Martínez‐González, Miguel Ángel; Martí, Amelia; Salas‐Salvadó, Jordi; Castañer, Olga; Fernández‐Aranda, Fernando; Torre, Rafael de la

doi:10.1016/j.clnu.2021.07.020

Cited by 25 publications

(43 citation statements)

References 87 publications

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“…An important instrument developed in the framework of this activity was the PREDIMED PLUS questionnaire aimed at assessing adherence to the MD ( 41 ). The questionnaire has been used widely in a number of EU countries ( 42 – 44 ). In a recent article focused on the evaluation of dietary changes during the COVID-19 pandemic, we adapted and tested the PREDIMED PLUS in the Italian context ( 33 ).…”

Section: Methodsmentioning

confidence: 99%

Nutrition Knowledge as a Driver of Adherence to the Mediterranean Diet in Italy

Aureli

Rossi

2022

Front. Nutr.

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BackgroundAn optimal Nutrition knowledge (NK) among the population could result in greater Adherence to the Mediterranean Diet (AMD), a recognized dietary pattern capable of preventing chronic food-related diseases. This study aimed to evaluate the association between NK and AMD in Italy.MethodsA national representative sample of 2,869 adults took part in an assessment that was carried out through a self-administrated questionnaire including sections relating to NK and AMD. AMD was evaluated following the PREDIMED PLUS methodology. Descriptive statistics were provided, and ordinal measures of NK score and AMD were calculated based on quartiles of the quantitative scores. A contingency analysis was performed to check associations between variables.ResultsIn Italy, the average NK score was 50 ± 13.3, equivalent to 56.8% of correct answers. The average value of AMD was 6.8, corresponding to 40% of the maximum score with 31.4% of the population demonstrating low AMD, 31.3% in the lower-middle range, 24% in the medium-high range, and only 13.3% reporting a high AMD. A significant association between NK and AMD was found; respondents who reported the lowest AMD corresponded to those with the lowest NK (36.7%; p < 0.05) and similarly, those with the highest level of adherence to MD also achieved the highest NK scores (41.7%; p < 0.05).ConclusionThis study showed that AMD in Italy is generally low, and the strong association between NK and AMD demonstrated that there is a clear connection between a healthy dietary pattern and the nutrition literacy of the population. Those with the highest AMD corresponded to the highest NK and, conversely, those with the lowest AMD displayed the lowest NK. The study also highlighted that socioeconomic aspects were strong determinants of both AMD and NK.

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Section: Methodsmentioning

confidence: 99%

Nutrition Knowledge as a Driver of Adherence to the Mediterranean Diet in Italy

Aureli

Rossi

2022

Front. Nutr.

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“…Observational studies suggest a beneficial effect of the Mediterranean diet on older adults’ global cognition[34]. A recent longitudinal prevention trial showed that better adherence to an energy-restricted Mediterranean diet is associated with improved global cognition three years later[9]. However, our analysis of bi-directional MR for single-food intake scores and cognitive performance mainly supports the reverse association, where cognitive function influences nutrition.…”

Section: Discussionmentioning

confidence: 56%

Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition

Granot‐Hershkovitz

Bressler

et al. 2022

Preprint

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INTRODUCTION We studied the replication and generalization of previously identified metabolites potentially associated with global cognitive function in multiple race/ethnicities and assessed the contribution of diet to these associations. METHODS: We tested metabolite-cognitive function associations in U.S.A. Hispanic/Latino adults (n= 2,222) from the Community Health Study/ Study of Latinos (HCHS/SOL) and in European (n=1,365) and African (n=478) Americans from the Atherosclerosis Risk In Communities (ARIC) Study. We applied Mendelian Randomization (MR) analyses to assess causal associations between the metabolites and cognitive function and between Mediterranean diet and cognitive function. RESULTS: Six metabolites were consistently associated with lower global cognitive function across all studies. Of these, four were sugar related (e.g., ribitol). MR analyses provided weak evidence for a potential causal effect of ribitol on cognitive function and bi-directional effects of cognitive performance on diet. DISCUSSION Several diet-related metabolites were associated with global cognitive function across studies with different race/ethnicities.

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“…The reasons for excluding full-text records were not a prospective cohort design ( n = 88) and not using MetS as a combined factor ( n = 4). Ultimately, 30 relevant prospective studies included in the qualitative synthesis ( Yaffe et al, 2004 , 2007 ; Xiong et al, 2006 ; Komulainen et al, 2007 ; van den Berg et al, 2007 ; Ho et al, 2008 ; Knopman et al, 2009 ; Yaffe et al, 2009 ; Akbaraly et al, 2010 ; Lee et al, 2010 ; Raffaitin et al, 2011 ; Creavin et al, 2012 ; Katsumata et al, 2012 ; McEvoy et al, 2012 ; Liu et al, 2013 ; Watts et al, 2013 ; Dearborn et al, 2014 ; Harrison et al, 2015 ; Gallagher et al, 2016 ; Viscogliosi et al, 2016 , 2017 ; Neergaard et al, 2017 ; Overman et al, 2017 ; Shigaeff et al, 2017 ; Bangen et al, 2019 ; Kazlauskaite et al, 2020 ; Przybycien-Gaweda et al, 2020 ; Soldevila-Domenech et al, 2021 ; Wu and Chen, 2021 ; Wang et al, 2021 ).…”

Section: Resultsmentioning

confidence: 99%

Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis

et al. 2022

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The aim of this review is to investigate the association between metabolic syndrome (MetS) and cognitive decline in distinct cognitive domains, and to perform a complementary study description through the bibliometric analysis. PubMed and Scopus databases were searched from inception to 15 December 2021 to identify longitudinal studies that examined the association of MetS with incident decline, in order to prevent reverse causality. The Preferred Reporting Items for Systematic Review and Meta-Analysis checklist was used to conduct the present systematic review. Thirty studies were included and results were analyzed across the cognitive domains of global cognition, memory, executive functions, attention, visuoconstructive abilities, and language. The majority of the studies reviewed did not report statistically significant results for most cognitive domains investigated, and decline in specific cognitive domains was not consistently associated with the presence of MetS. Meta-analyses were not conducted due to the high degree of between-study heterogeneity regarding the MetS definitions, the cognitive domains examined, the specific tests used for each cognitive domain and the different measures of association used. Bibliometric analysis revealed that most studies are conducted by research teams from USA and China, and that cognitive tasks that reflect real-life abilities are rarely examined. Future studies should employ larger sample sizes, longer follow-up periods, a global consensus for MetS definition and standardized tests of the above mentioned cognitive domains as well as problem-solving tasks with high sensitivity and specificity to clarify the impact of MetS on cognition and its underlying mechanisms.

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Interplay between cognition and weight reduction in individuals following a Mediterranean Diet: Three-year follow-up of the PREDIMED-Plus trial

Cited by 25 publications

References 87 publications

Nutrition Knowledge as a Driver of Adherence to the Mediterranean Diet in Italy

Nutrition Knowledge as a Driver of Adherence to the Mediterranean Diet in Italy

Plasma metabolites associated with cognitive function across race/ethnicities affirming the importance of healthy nutrition

Metabolic syndrome and cognition: A systematic review across cognitive domains and a bibliometric analysis

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