Interobserver variability of optic disk variables measured by confocal scanning laser tomography

Iester, Michele; Mikelberg, Frederick S.; Courtright, Paul; Burk, Reinhard; Jonas, Jost B.; Weinreb, Robert N.; Zangwill, Linda M.

doi:10.1016/s0002-9394(01)00938-2

Cited by 55 publications

(36 citation statements)

References 17 publications

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“…237,248 In the interobserver study, cup shape measure ranked third best, but in the intraobserver study, AJK and DBH showed it to be the most repeatable and second most repeatable parameter, respectively. This parameter is considered particularly important, since it has been previously shown to have good sensitivity and specificity for diagnosing glaucoma and, compared with the other parameters, it is considered suitable for monitoring progression because it is independent of change in the reference plane.…”

Section: Discussionmentioning

confidence: 98%

“…The same pattern was found for the GDx, although the magnitude was far less. The use of stereo-photographs has been shown to improve repeatability of HRT parameters, 248 which might be an especially useful aid for analysing discs with margins that are considered difficult to define.…”

Section: Discussionmentioning

confidence: 99%

“…247,248 However, this aid was not incorporated in this study, the aim of which was to reproduce a realistic clinical environment, where such photographs are routinely not available.…”

Section: Hrtmentioning

confidence: 99%

See 2 more Smart Citations

The effectiveness of the Heidelberg Retina Tomograph and laser diagnostic glaucoma scanning system (GDx) in detecting and monitoring glaucoma

Kwartz

Henson²,

Harper³

et al. 2005

Health Technol Assess

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

The effectiveness of the Heidelberg Retina Tomograph and laser diagnostic glaucoma scanning system (GDx) in detecting and monitoring glaucoma

Kwartz

Henson²,

Harper³

et al. 2005

Health Technol Assess

View full text Add to dashboard Cite

show abstract

“…[3][4][5][6][7][8] However, there are two weak points in the HRT methodology: the reference plane and the contourline. 9 The observer has to draw the contourline on the outer edge of the rim and then the system is able to find a reference plane, which is fundamental to calculate some of the HRT parameters, such as rim area or volume, cup area, or volume, etc.…”

Section: Introductionmentioning

confidence: 99%

Detection of glaucomatous optic nerve head by using Heidelberg topographic maps

Iester

Zanini

Vittone

et al. 2006

Eye

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“…An automated method we originally developed for segmentation of the ONH in images provided by scanning-lasertomography (SLT) 4 is limited by noise, non-uniform illumination, low contrast and presence of blood vessels. Inspired by recent medical research 5 we developed a more advanced method improving our previous algorithm by using registered multimodal retinal images. The multimodal approach combines SLT-images with color fundus photographs (CFP).…”

Section: Introductionmentioning

confidence: 99%

Optic nerve head segmentation in multimodal retinal images

et al. 2005

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An established method for glaucoma diagnosis is the morphological analysis of the optic nerve head (ONH) by the scanning-laser-tomography (SLT). This analysis depends on prior manual outlining of the ONH. The first automated segmentation method that we developed is limited in its reliability by noise, non-uniform illumination and presence of blood vessels. Inspired by recent medical research we developed a new algorithm improving our previous method by segmenting in registered multimodal retinal images. The multimodal approach combines SLT-images with color fundus photographs (CFP). The first step of the algorithm, the registration, is based on gradient-image mutual information maximization using controlled random search as the optimization procedure. The kernel of the segmentation module consists in the anchored active contours. The initial contour is obtained from the CFP. The points the initial curve should be attracted to, the anchors, are constrained by the Hough transform applied to a morphologically processed SLT-image. The false anchors are eliminated by masking out blood vessels that are extracted in the CFP. The method was tested on 174 multimodal image pairs. The overall performance of the system yielded 89% correctly segmented ONH, qualitatively evaluated comparing the automated contours with manual ones drawn by an experienced ophthalmologist. This represents an appreciable improvement in reliability (from 74% to 89%) compared to monomodal approach. The developed method is the basis for a promising tool for glaucoma screening.

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Interobserver variability of optic disk variables measured by confocal scanning laser tomography

Cited by 55 publications

References 17 publications

The effectiveness of the Heidelberg Retina Tomograph and laser diagnostic glaucoma scanning system (GDx) in detecting and monitoring glaucoma

The effectiveness of the Heidelberg Retina Tomograph and laser diagnostic glaucoma scanning system (GDx) in detecting and monitoring glaucoma

Detection of glaucomatous optic nerve head by using Heidelberg topographic maps

Optic nerve head segmentation in multimodal retinal images

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