“…The study was conducted using data collected inthe cohort GrippeNet.fr, a web-based participative study conducted in France (25).Developed by the French National Institute of Health and Medical Research (Inserm), Pierre and Marie Curie University (UPMC) and the French Institute for Public Health Surveillance (InVS), this project is part of a broader European study,Influenzanet (http://www.influenzanet.eu) (26), whichallows monitoring ILI evolution directly in the general population.The inclusion criteria to participate in the GrippeNet.fr study include: 1) residency in France 2) comprehension of the French language 3) access to the Internet. Upon registration, participants were asked to complete a baseline questionnaire covering demographic factors (age, gender), geographicalfactors (location of home and work/school expressed at themunicipality level), socio-economic factors (household size and composition, occupation, educational level, number of daily contacts with groups of patients, children or elderly, daily transportation means), 6 and health-related factors (height and weight, diet, vaccination status, pregnancy status, smoking habits,major risk conditions, and opinion about seasonal influenza vaccination evaluated over three levels ("positive", "negative" or "neutral").Subsequently, they were invited to describe weekly clinical symptoms during the flu season.…”