International Society for Heart and Lung Transplantation Donation After Circulatory Death Registry Report

Cypel, Marcelo; Levvey, B.; Raemdonck, Dirk Van; Erasmus, Michiel E.; Dark, John H.; Love, Robert B.; Mason, David P.; Glanville, Allan R.; Chambers, Daniel C.; Edwards, Leah B.; Stehlik, Josef; Hertz, Marshall I.; Whitson, B.A.; Yusen, Roger D.; Puri, Varun; Hopkins, P.; Snell, Greg; Keshavjee, Shaf

doi:10.1016/j.healun.2015.08.015

Cited by 170 publications

(146 citation statements)

References 16 publications

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“…In order to standardize the definitions around important times in DCD donation process, ISHLT DCD Working Group recommended the following times points and intervals (12). Table 3 and Figure 1 show schematic presentation of the time points and intervals recommended by ISHLT DCD Working Group (12).…”

Section: Definitions Of Witmentioning

confidence: 99%

“…Table 3 and Figure 1 show schematic presentation of the time points and intervals recommended by ISHLT DCD Working Group (12).…”

Section: Definitions Of Witmentioning

confidence: 99%

“…The use of lungs from donation after cardiocirculatory death (DCD) donors is one of the options to avoid organ shortage in LTx (3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16). The number of lung transplants performed from DCD donors is increasing.…”

Section: Introductionmentioning

confidence: 99%

“…The number of lung transplants performed from DCD donors is increasing. A recent International Society for Heart and Lung Transplantation (ISHLT) DCD Registry Report included 306 recipients among ten centers worldwide (12). Several centers published their experience, most of them with excellent or at least equal results compared to brain-dead donors (5,14,(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28).…”

Section: Introductionmentioning

confidence: 99%

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Donors after cardiocirculatory death and lung transplantation

İnci

2017

J. Thorac. Dis.

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Abstract:The number of patients actively awaiting lung transplantation (LTx) is more than the number of suitable donor lungs. The percentage of lung retrieval rate is lower when compared to other solid organs.The use of lungs from donation after cardiocirculatory death (DCD) donors is one of the options to avoid organ shortage in LTx. After extensive experimental research, clinical application of DCD donation is becoming wider. The results from most of the centers show at least equal survival rate compared to donors from brain death. This review paper will summarize experimental background and clinical experience from DCD donors.

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Section: Definitions Of Witmentioning

confidence: 99%

“…Table 3 and Figure 1 show schematic presentation of the time points and intervals recommended by ISHLT DCD Working Group (12).…”

Section: Definitions Of Witmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Donors after cardiocirculatory death and lung transplantation

İnci

2017

J. Thorac. Dis.

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“…It is estimated that only 15-20% of the standard, brain-dead donors fulfill the ideal criteria for lung donation (2). Lungs from non-standard donors, such as extended-criteria donors and those succumbing after cardiocirculatory arrest are now increasingly being used with similar early and late outcome results and freedom from chronic rejection (3,4). Chronic rejection, leading to CLAD, is the most common underlying etiology of late mortality following lung transplantation present in about 50% of patients at 5 years after transplantation (1).…”

Section: Introductionmentioning

confidence: 99%

Lung cancer: a rare indication for, but frequent complication after lung transplantation

Raemdonck¹,

Vos²,

Yserbyt³

et al. 2016

J. Thorac. Dis.

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Lung transplantation is an effective and safe therapy for carefully selected patients suffering from a variety of end-stage pulmonary diseases. Lung cancer negatively affects prognosis, particularly in patients who are no longer candidates for complete resection. Lung transplantation can be considered for carefully selected and well staged lung cancer patients with proven, lung-limited, multifocal, (minimally invasive) adenocarcinoma in situ (AIS) (previously called bronchioloalveolar cell carcinoma) causing respiratory failure. Despite a substantial risk of tumour recurrence (33-75%), lung transplantation may offer a survival benefit (50% at 5 years) with best palliation of their disease. Reports on lung transplantation for other low-grade malignancies are rare. Lung transplant candidates at higher risk for developing lung cancer [mainly previous smokers with chronic obstructive lung disease (COPD) and idiopathic pulmonary fibrosis (IPF) or older patients] should be thoroughly and repeatedly screened for lung cancer prior to listing, and preferably also during waiting list time if longer than 1 year, including the use of PET-CT scan and EBUS-assisted bronchoscopy in case of undefined, but suspicious pulmonary abnormalities. Double-lung transplantation should now replace single-lung transplantation in these high-risk patients because of a 6-9% prevalence of lung cancer developing in the remaining native lung. Patients with unexpected, early stage bronchial carcinoma in the explanted lung may have favourable survival without recurrence. Early PET-CT (at 3-6 months) following lung transplantation is advisable to detect early, subclinical disease progression. Donor lungs from (former) smokers should be well examined at retrieval. Suspicious nodules should be biopsied to avoid grafting cancer in the recipient. Close follow-up with regular visits and screening test in all recipients is needed because of the increased risk of developing a primary or secondary cancer in the allograft from either donor or recipient origin.

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Organ Donation After Euthanasia

Matas

Payne

2020

JAMA Surg

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Health, Food Chain Safety and Environment. Act on euthanasia. Wet betreffende de euthanasie. Accessed July 19, 2019. https://www.health. belgium.be/sites/default/files/uploads/fields/ fpshealth_theme_file/loi20020528mb_frnl.pdf 15. Government of the Netherlands; Ministry of Health, Welfare and Sport; Ministry of Justice and Security. Termination of life on request and assisted suicide act. Wet toetsing levensbeëindiging op verzoek en hulp bij zelfdoding. Accessed July 19, 2019.

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International Society for Heart and Lung Transplantation Donation After Circulatory Death Registry Report

Cited by 170 publications

References 16 publications

Donors after cardiocirculatory death and lung transplantation

Donors after cardiocirculatory death and lung transplantation

Lung cancer: a rare indication for, but frequent complication after lung transplantation

Organ Donation After Euthanasia

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