In the Chinese Year of the Dog, we are pleased to present to you the first issue of the new journal we have organized: Animal Models and Experimental Medicine (AMEM).Why do we need a new journal in this area? Laboratory animal sciences is an emerging interdisciplinary subject, which integrates theories and methods from many disciplines, including biology, medicine, pharmacy, veterinary, bioengineering, biomedical engineering, etc. In recent years, many outstanding papers based on laboratory animals have been published around the world, highlighting how laboratory animal sciences has, among other things, provided systematic biological materials and pertinent technologies for the development of related disciplines; integration into many frontier disciplines; development of new disciplines such as comparative medicine, experimental animal medicine, and comparative biology; and supported development in fields such as life sciences, medicine, food, environment and aerospace. However, there are very few specialized journals in this field, and their impact is very limited. The journal has cooperated with Wiley, the third largest publishing group in the world. Our international editorial team is composed of well-known scientists from China and abroad, and promises to quickly review submitted manuscripts and to make fair decisions. We welcome and encourage the submission of high-quality, original papers, and look forward to publishing more insightful research articles in the journal.