International multicentre prospective study on microwave ablation of liver tumours: preliminary results

Lloyd, David M.; Lau, Kwan N.; Welsh, Fenella; Lee, Kit Fai; Sherlock, David; Choti, Michael A.; Martinie, John B.; Iannitti, David A.

doi:10.1111/j.1477-2574.2011.00338.x

Cited by 50 publications

(42 citation statements)

References 38 publications

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“…The safety of VLA for HCC had so far been reported for series of no more than 267 patients treated with RFA, and 203 treated with MWA . The vast majority of the complications described to date (in 2% to 45% of patients treated with VL RFA, and in 16% to 62% of those treated with VL MWA) were minor. The use of MWA has nonetheless been widely questioned because of the potentially higher risk of major biliary damage associated with the greater amount of energy delivered.…”

Section: Discussionmentioning

confidence: 99%

Videolaparoscopic microwave ablation in patients with HCC at a European high‐volume center: Results of 815 procedures

Cillo

Bertacco

Fasolo

et al. 2019

Journal of Surgical Oncology

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Background: Videolaparoscopic (VL) microwave ablation (MWA) is not included in most of the international guidelines as a therapeutic option for hepatocellular carcinoma (HCC). Aim of this study was to assess the safety of VL MWA in patients with HCC for whom resection or percutaneous ablation is unsuitable. Methods: A retrospective analysis was performed on a prospective database of patients with HCC treated with VL MWA at our institution from 2009 to 2016. Patient demographics, operational characteristics, and complications were recorded. Statistical analysis was performed to identify safety profile, overall survival and recurrence rate. Results: A total of 815 VL MWA were performed in 674 patients with a mean age of 64 years. Patients had a mean Model for End‐stage Liver Disease score of 10 (±3); 32.8% were Child B, 44.1% Barcelona Clinic Liver Cancer B‐C. Perioperative mortality was 0.4%. Overall morbidity was 30.8%, with Dindo‐Clavien complications ≥3 in 2%. The median length of stay was 2 days. In 43.1% VL MWA was the first‐line therapy. Overall 1‐, 3‐, and 5‐year survival rates were 81.9%, 54.9%, and 35.9%. Conclusions: The present is the largest series of VL ablation and the bigger number of patients with HCC treated with MW reported nowadays. It confirms the safety of a minimally invasive procedure for patients with HCC when resection or percutaneous ablation is not feasible.

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Section: Discussionmentioning

confidence: 99%

Videolaparoscopic microwave ablation in patients with HCC at a European high‐volume center: Results of 815 procedures

Cillo

Bertacco

Fasolo

et al. 2019

Journal of Surgical Oncology

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“…More recent antenna designs are now available to create more focal, shorter ablation zones that are centered more toward the tip of the antenna (14,76–78). Such antennas are particularly helpful when treating small or peripheral tumors.…”

Section: Current Techniques For Treating Liver Cancer Using Microwavementioning

confidence: 99%

Microwave ablation in primary and secondary liver tumours: technical and clinical approaches

Meloni¹,

Chiang

Laeseke

et al. 2016

International Journal of Hyperthermia

102

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Thermal ablation is increasingly utilized in the treatment of primary and metastatic liver tumors, both as curative therapy and as a bridge to transplantation. Recent advances in high-powered microwave ablation systems have allowed physicians to realize the theoretical heating advantages of microwave energy compared to other ablation modalities. As a result, there is a growing body of literature detailing the effects of microwave energy on tissue heating, as well as its effect on clinical outcomes. This article will discuss the relevant physics, review current clinical outcomes and then describe the current techniques used to optimize patient care when using microwave ablation systems.

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“…In the last years alternative techniques have been developed, as ablation by radio frequencies, chemoembolization, radioembolization, magnetic chemotherapy and cryo-ablation, for local treatment of the liver tumour [8]- [12].…”

Section: Introductionmentioning

confidence: 99%

Dielectric Properties of Human Normal and Malignant Liver Tissue: A Non-Equilibrium Thermodynamics Approach

Farsaci¹,

Russo²,

Ficarra³

et al. 2015

OALib

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In this paper we will show the possibility of studying physical properties and irreversible phenomena that occur in biological tissues by applying the dielectric Kluitenberg's non-equilibrium thermodynamic theory. Namely, we shall use some recent extensions of this theory that allows deducing its main characteristic parameters from experimental measurements. We determine frequency spectrum for phenomenological and state coefficients of the non-equilibrium thermodynamic approach. Applying these results to the study of human liver tumor and normal liver we show, for comparison, that it is possible to determine the difference, in some detail, of the amount of single irreversible phenomena occurring inside them.

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International multicentre prospective study on microwave ablation of liver tumours: preliminary results

Cited by 50 publications

References 38 publications

Videolaparoscopic microwave ablation in patients with HCC at a European high‐volume center: Results of 815 procedures

Videolaparoscopic microwave ablation in patients with HCC at a European high‐volume center: Results of 815 procedures

Microwave ablation in primary and secondary liver tumours: technical and clinical approaches

Dielectric Properties of Human Normal and Malignant Liver Tissue: A Non-Equilibrium Thermodynamics Approach

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