International Multicenter Term PROM Study: Evaluation of predictors of neonatal infection in infants born to patients with premature rupture of membranes at term

Seaward, P. G. R.; Hannah, Mary E.; Myhr, Terri L.; Farine, Dan; Ohlsson, Arne; Wang, Elaine E.; Hodnett, Ellen; Haque, Khalid N.; Weston, Julie; Ohel, Gonen

doi:10.1016/s0002-9378(98)70056-0

Cited by 105 publications

(79 citation statements)

References 9 publications

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“…In an evaluative study derived from international multicentre Term Prelabor Rupture of Membranes Study, incidence of chorioamnionitis was 7% and postpartum fever was 3% whereas in our study, there were no cases of either postpartum fever or chorioamnionitis. 17 This difference could be due to the large difference in sample size in the two studies and probably due to early induction and the use of prophylactic antibiotics at the time of diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Induction of Labour in Prelabour Rupture of Membranes with or without Cervical Ripening with Prostaglandin E2

Aryal¹,

Karki

2014

J Lumbini Med Coll

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Original Research Article -------------------------------------------ABSTRACT:Objective: To compare the outcome of induction of labour with titrated dose of oxytocin with or without pre induction cervical ripening using prostaglandin E2. Methods: This is a prospective study. Sixty women with prelabour rupture of membranes (PROM) and Bishops score of less than six were randomly assigned to either immediate induction with intravenous oxytocin drip or induction with intravenous oxytocin drip preceded by cervical priming with prostaglandin E2 (PGE2) gel 0.5mg instilled intracervically. These two groups were compared regarding the mode of delivery, induction to delivery interval and maternal and neonatal morbidities. Results: Cervical priming with PGE2 resulted in lesser number of caesarean section (5 Vs. 12) and lower incidence of meconium stained liquor (n=6 Vs. n=2). Induction to vaginal delivery interval was shorter when cervical priming was done (5.4 hrs Vs 7.9 hrs). The maternal morbidity was negligible (<1%) in both the groups. The number of neonates with birth asphyxia (n=2) and the need for their resuscitation (n=2) was more in the oxytocin group but the need of antibiotics for the neonates was more in PGE2 group (5% Vs. 3%). Conclusion: Induction of labor with oxytocin, with or without cervical priming with vaginal PGE2 gel, are both reasonable options in cases of PROM, since they result in statistically non significant rates of maternal and neonatal morbidities and caesarean section. Cervical priming with prostaglandin results in higher rate of vaginal delivery and shorter induction to vaginal delivery interval and this is viewed as an advantage to the mother. Keywords: induced labor • premature rupture • oxytocin • prostaglandin • cervical ripening -------------------------------------------

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Section: Discussionmentioning

confidence: 99%

Induction of Labour in Prelabour Rupture of Membranes with or without Cervical Ripening with Prostaglandin E2

Aryal¹,

Karki

2014

J Lumbini Med Coll

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“…One study which looked at this showed that mothers testing positive for GBS combined with PROM had a significantly increased the risk of sepsis compared to unknown or negative GBS status odds ratio (OR) 0.308 (95% confidence interval [CI]: 2.02 to 4.68). 3 This dangerous combination was recognized by the doctors in the audit and they would have performed screening blood analysis in 100% of these babies even if it was not the policy to have done so. In fact in one case the baby was screened and commenced on prophylactic antibiotics prior to the inflammatory markers coming back.…”

Section: Discussionmentioning

confidence: 99%

Prolonged rupture of membranes in term infants: should all babies be screened?

Flannigan

Hogan²

2010

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“…, 12 which concluded that E.coli and Staphylococcus infection were significantly associated with PROM, although it was multifactorial. It remains to be seen whether these are a direct cause of PROM or are simply surrogate markers for another not yet identified pathogenic process.…”

Section: Methods Of Studymentioning

confidence: 99%

A Study on the Relationship between High Vaginal Swab Culture and Neonatal Sepsis in Prelabour Rupture of Membranes at Term

.Gopal¹

2017

jmscr

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International Multicenter Term PROM Study: Evaluation of predictors of neonatal infection in infants born to patients with premature rupture of membranes at term

Cited by 105 publications

References 9 publications

Induction of Labour in Prelabour Rupture of Membranes with or without Cervical Ripening with Prostaglandin E2

Induction of Labour in Prelabour Rupture of Membranes with or without Cervical Ripening with Prostaglandin E2

Prolonged rupture of membranes in term infants: should all babies be screened?

A Study on the Relationship between High Vaginal Swab Culture and Neonatal Sepsis in Prelabour Rupture of Membranes at Term

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