International Expert Panel Consensus on Fat Grafting of the Breast

Nava, Maurizio; Blondeel, Phillip; Botti, Giovanni; Casabona, Francesco; Catanuto, Giuseppe; Clemens, Mark W.; Fazio, Domenico De; Vita, Roy De; Grotting, James C.; Hammond, Dennis C.; Harris, Paul A.; Montemurro, Paolo; Munhoz, Alexandre Mendonça; Nahabedian, Maurice Y.; S, Pompei; Rancati, Alberto; Rigotti, Gino; Salgarello, Marzia; Scaperrotta, Gianfranco; Spanò, Andrea; Stan, Costantin; Rocco, Nicola

doi:10.1097/gox.0000000000002426

Cited by 42 publications

(31 citation statements)

References 106 publications

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“…In total, 74 patients (21.6%) sustained a clinically apparent complication in the postoperative clinical course. Following the international expert panel consensus on fat grafting of the breast, 16 complications were grouped according to the widely used Clavien‐Dindo classification 24,25 . In 65 cases (19.1%), a class 1 complication was recorded, which includes any deviation from the standard postoperative course such as the administration of antiemetics or fluid management.…”

Section: Resultsmentioning

confidence: 99%

“…Complications such as resorption, the formation of oil cysts, clinically apparent infection, and wound healing problems were documented. Key outcome parameters were analysed for each patient in accordance with the recently released international expert consensus on fat grafting of the breast, 16 documenting the complications according to the Clavien‐Dindo classification, 24,25 outcome, and the number of fat grafting sessions needed to obtain the optimal result, noting that every single procedure had the aim of reaching the desired volume without follow‐up procedures.…”

Section: Methodsmentioning

confidence: 99%

“…Patients were operated under general anaesthesia. Tumescent solution according to Klein 16,26 or Illoz 27 was used for infiltration before fat harvest. After 15 minutes, fat was harvested using the low‐pressure pump‐assisted system (BodyJet, HumanMed, Germany) with a 5‐mm‐diameter cannula, collecting the fat in a sterile closed filtration chamber connected to a standard surgical vacuum.…”

Section: Methodsmentioning

confidence: 99%

“…Uncritical use of antibiotic substances should be avoided at all times because it contributes to the increasing global burden of drug resistance 15 . However, no distinct guidelines or protocols concerning perioperative antibiotic therapy have been defined in the literature so far despite the recent release of an international expert consensus on fat grafting of the breast 16 . On the other hand, no benefit of prolonged antibiotic prophylaxis was found in recent literature regarding reduction mammaplasty 17 and primary and secondary aesthetic breast surgery, 18 with conflicting data on mamma reconstruction 19 …”

Section: Introductionmentioning

confidence: 99%

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Prolonged antibiotic prophylaxis in tissue reconstruction using autologous fat grafting: Is there a benefit for wound healing?

Morandi

Winkelmann

Dostal

et al. 2021

International Wound Journal

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Fat grafting is a well‐established method in plastic surgery. Despite many technical advances, standardised recommendations for the use of prophylactic antibiotics in fat grafting are not available. This retrospective multicentre study aims to analyse the use of prophylactic antibiotics in fat grafting and to compare complication rates for different protocols. A retrospective medical chart review of 340 patients treated with fat grafting of the breast from January 2007 to March 2019 was performed in three plastic surgery centres. Complications, outcomes, and antibiotic regimes were analysed. The Clavien‐Dindo classification was applied. All patients received perioperative antibiotic prophylaxis: 33.8% (n = 115) were treated with a single shot (group 1), 66.2% (n = 225) received a prolonged antibiotic scheme (group 2). There was no significant difference in the number of sessions (P = .475). The overall complication rate was 21.6% (n = 75), including graft resorption, fat necrosis, infection, and wound healing problems. Complication rates were not significantly different between groups. Risk factors for elevated complication rates in this specific patient group are smoking, chemotherapy, and irradiation therapy. The complication rate for lipografting of the breast is low, and it is not correlated to the antibiotic protocol. The use of prolonged prophylactic antibiotics does not lower the complication rate.

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Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prolonged antibiotic prophylaxis in tissue reconstruction using autologous fat grafting: Is there a benefit for wound healing?

Morandi

Winkelmann

Dostal

et al. 2021

International Wound Journal

View full text Add to dashboard Cite

show abstract

“…Low-pressure suction (<250 mmHg) appears to increase adipocyte viability (49). Various devices are available to assist fat harvest, however none has been proven to be superior and surgeons and teams should have specific training in the preferred harvest technique and evaluate safety and outcomes 50 .…”

Section: Harvestingmentioning

confidence: 99%