International Expansion of the Use of Pharmacotherapies for the Treatment of Opioid Dependence

Kresina, Thomas F.

doi:10.4172/2161-1459.s5-001

Cited by 6 publications

(6 citation statements)

References 65 publications

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“…On the other hand, different treatment modalities, especially with methadone, have to be accompanied by behavioral treatment. Research has in fact shown the absence of the latter to increase the frequency of relapse ( 32 ).…”

Section: Discussionmentioning

confidence: 99%

The Effects of Family-Centered Problem-Solving Education on Relapse Rate, Self Efficacy and Self Esteem Among Substance Abusers

Habibi

Nasrabadi

Hamedan

et al. 2016

Int J High Risk Behav Addict

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Background:The success of drug abuse treatment and relapse prevention methods depends widely on not only pharmaceutical and non-pharmaceutical therapies but also self efficacy and self esteem promotion.Objectives:The current study attempted to clarify the effects of Problem Solving Education (PSE) on relapse rate, self efficacy and self esteem among drug abusers.Patients and Methods:This non-controlled clinical trial (quasi-experimental) assessed 60 opium and heroin abusers who were willing to quit and were referred to the Mehr Center of Addiction Treatment and Rehabilitation Facility. The patients were allocated to two groups of 30 (intervention and control groups). While both groups received the routine care of the clinic, the intervention group also attended eight 45-minute family-centered PSE sessions. The Coopersmith Self esteem Inventory and Quit Addiction Self efficacy Questionnaire were filled out for all subjects before and after the intervention. Drug relapse was investigated four times with two-week intervals. The two groups were compared using chi-square and Student’s-t tests. Logistic regression analysis was applied to determine factors affecting drug relapse.Results:A total of 45 individuals (21 and 24 in the intervention and control groups, respectively) completed the study. At baseline, the two groups had no significant difference regarding their mean scores of self esteem and self efficacy (P = 0.692 and 0.329, respectively). After the intervention, however, the mean changes of self esteem scores were 20.10 ± 3.75 for the intervention group and 4.50 for the control group (P < 0.001). The mean changes of self efficacy scores in the mentioned groups were 34 34.17 ± 5.19 and 9.03± 2.04, respectively (P < 0.001). Drug relapse after two weeks was correlated with age (OR = 1.216; P = 0.026; 95% CI: 1.024-1.445) and implementation of the intervention (OR = 0.036; P = 0.003; 95% CI: 0.004-0.322).Conclusions:According to our findings, supplementing drug abuse treatment with cognitive behavior therapy, particularly PSE, can reduce relapse rate and enhance self efficacy and self esteem among patients.

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Section: Discussionmentioning

confidence: 99%

The Effects of Family-Centered Problem-Solving Education on Relapse Rate, Self Efficacy and Self Esteem Among Substance Abusers

Habibi

Nasrabadi

Hamedan

et al. 2016

Int J High Risk Behav Addict

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“…Methadone is the preferred pharmacotherapy for resource limited setting because of its lower cost compared to other medications. Globally since 2000, there has been a rapid expansion of medication-assisted treatment, mainly using methadone, in the context of HIV prevention, care and treatment programs [88]. The integration of substance abuse treatment and HIV care and treatment is an effective and cost efficient health service platform to provide care and treatment for HCV/HIV co-infection in a resource limiting setting [89].…”

Section: Pharmacologic Treatments For Substance Use Disordersmentioning

confidence: 99%

Issues in the Care and Treatment of HCV/HIV Co-Infection for Key Populations in Resource-Constrained Settings

Kresina¹,

Lubran²,

Clark³

2014

Health

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Globally, the epidemic of hepatitis virus infection is increasing in the context of common viral transmission routes with the Human Immunodeficiency Virus (HIV). Thus, co-infection with both hepatitis virus and HIV is becoming a common occurrence, particularly for key populations. Studies of key populations, people who inject drugs, sex workers, transgendered individuals and men having sex with men, report high levels of illicit drug and/or alcohol use along with limited access to health care and medical treatment. Without the medical management of co-occurring substance use disorders and hepatitis C virus (HCV) infection, a significant proportion of this population with HCV/HIV co-infection will progress to chronic liver disease then subsequently end-stage liver disease. Thus, access to comprehensive care and treatment, including HCV testing with subsequent care and treatment of acute/chronic HCV infection is essential to address the global burden of disease. Increased efforts are needed globally to address the barriers to comprehensive care and treatment for key populations with HCV/HIV co-infection.

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“…However, a strong research base in Western countries has resulted in the development of evidence-based medical practices using opioid agonists in maintenance treatment regimens and opioid antagonists in relapse prevention strategies. The recognition of these evidence-based medical treatment for opioid abuse and dependence has resulted in a substantial global increase in the medical use of opioid agonists and psychotropic medications to address opioid dependence [28–30]. This increase is particularly evident in the initiation of new pharmacotherapy programs in regions of Europe, North America, Africa, Asia, and Oceania.…”

Section: Substance Abuse Treatment As Hiv Prevention and Part Of Tmentioning

confidence: 99%

Substance Abuse Treatment, HIV/AIDS, and the Continuum of Response for People Who Inject Drugs

Kresina

Lubran

Clark

et al. 2012

Advances in Preventive Medicine

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The continuum of response (CoR) to HIV/AIDS is a framework for implementation of HIV prevention, care, and treatment programs based on a national strategic plan for HIV/AIDS services. The CoR for people who inject drugs (PWID) is an important extension of the developed CoR to HIV/AIDS. The CoR-PWID employs stakeholders who together plan, develop, pilot, and provide a full range of services that address the various prevention, care/support, and treatment needs of people, families, and communities infected or affected by HIV/AIDS and injection drug use. The CoR-PWID comprises a broad range of services that include but are not limited to the World Health Organization priority interventions for HIV/AIDS prevention, treatment, and care in the health sector and the package of essential interventions for the prevention, treatment, and care of HIV for people who inject drugs. Implementation of these well-defined, essential prevention, care/support, and treatment services, in addition to locally defined needed services, in a coordinated fashion is important to clients, their families, and communities. The CoR-PWID is, therefore, a necessary framework essential for service development for countries that address HIV/AIDS in populations of PWID.

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International Expansion of the Use of Pharmacotherapies for the Treatment of Opioid Dependence

Cited by 6 publications

References 65 publications

The Effects of Family-Centered Problem-Solving Education on Relapse Rate, Self Efficacy and Self Esteem Among Substance Abusers

The Effects of Family-Centered Problem-Solving Education on Relapse Rate, Self Efficacy and Self Esteem Among Substance Abusers

Issues in the Care and Treatment of HCV/HIV Co-Infection for Key Populations in Resource-Constrained Settings

Substance Abuse Treatment, HIV/AIDS, and the Continuum of Response for People Who Inject Drugs

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