2020
DOI: 10.1136/bmjopen-2019-035246
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International epidemiology databases to evaluate AIDS (IeDEA) in sub-Saharan Africa, 2012–2019

Abstract: PurposeThe objectives of the International epidemiology databases to evaluate AIDS (IeDEA) are to (i) evaluate the delivery of combination antiretroviral therapy (ART) in children, adolescents and adults in sub-Saharan Africa, (ii) to describe ART regimen effectiveness, durability and tolerability, (iii) to examine HIV-related comorbidities and coinfections and (iv) to examine the pregnancy-related and HIV-related outcomes of women on ART and their infants exposed to HIV or ART in utero or via breast milk.Part… Show more

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Cited by 73 publications
(78 citation statements)
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“…We followed a cohort of HIV-positive adolescents who enrolled in HIV care at the Rahima Moosa Mother and Child Hospital in Johannesburg, South Africa. The clinic participates in the International epidemiology Databases to Evaluate AIDS in Southern Africa (IeDEA-SA) and regularly transfers de-> identified routine clinical data of HIV-positive mothers, children and adolescents to the IeDEA-SA data centres at the University of Cape Town and the University of Bern [43].…”
Section: Methodsmentioning
confidence: 99%
“…We followed a cohort of HIV-positive adolescents who enrolled in HIV care at the Rahima Moosa Mother and Child Hospital in Johannesburg, South Africa. The clinic participates in the International epidemiology Databases to Evaluate AIDS in Southern Africa (IeDEA-SA) and regularly transfers de-> identified routine clinical data of HIV-positive mothers, children and adolescents to the IeDEA-SA data centres at the University of Cape Town and the University of Bern [43].…”
Section: Methodsmentioning
confidence: 99%
“…ART programme data covering the period from Jan 1, 2004, to Dec 31, 2017, were provided by the International Epidemiology Database to Evaluate AIDS (IeDEA) Southern Africa collaboration. 11 Mental health records covering the period from Jan 1, 2010 (the start of electronic collection of records), to Dec 31, 2017, were provided by the Western Cape Provincial Health Data Centre. 12 This service links patient information from several routine health information systems, including hospital discharge summaries (with International Classification of Diseases, 10th Revision [ICD-10] diagnoses) and pharmacy records, via a unique identifier.…”
Section: Methodsmentioning
confidence: 99%
“…IeDEA is funded by the U.S. National Institutes of Health to collect globally diverse clinical observational HIV treatment data from PLWH. HIV care and treatment sites participating in IeDEA are primarily public-sector health facilities and are comprised of both academic and community-based hospitals and health centers [39,40]. Because IeDEA sites have the capacity to routinely contribute electronic data, these sites may function at a higher level than HIV treatment sites not participating in IeDEA.…”
Section: Methodsmentioning
confidence: 99%
“…The IeDEA consortium is a global research consortium established in 2006 of HIV treatment sites in seven geographic regions: Central Africa; East Africa; South Africa; West Africa; the Asia-Pacific; the Caribbean, Central, and South America (CCASAnet); and North America (NA-ACCORD) [ 36 39 ]. IeDEA is funded by the U.S. National Institutes of Health to collect globally diverse clinical observational HIV treatment data from PLWH.…”
Section: Methodsmentioning
confidence: 99%