Internally Administered Radioisotopes

Loevinger, Robert; Holt, JD; Hine, Gerald J.

doi:10.1016/b978-1-4832-3257-7.50025-1

Cited by 59 publications

(32 citation statements)

References 21 publications

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“…Therefore direct measurements can provide more accurate bio-kinetic data of activity as well as the absorbed doses. NCRP also recommended about the direct measurements of the activity and absorb doses [13]. In this study we have demonstrated a direct method to obtain bio-distribution and the bio-kinetics of 99m Tc-DTPA in normal Bangladeshis.…”

Section: Resultsmentioning

confidence: 98%

Bio-Distribution and Dosimetry of a Renal Agent in Normal Bangladeshi Subjects

et al. 2013

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Radiation absorbed dose estimation was performed on eleven normal patients who were in a process of routine diagnostic investigation of the renal function. Bio-kinetics and bio-distribution of 99m Tc-DTPA in patients was evaluated by dual-head gamma camera imaging and blood-plasma sample counting method. Radiation dose estimations were performed using standard MIRD techniques and biodistribution of different organ was estimated by drawing region of interest (ROI) according to MIRD phantom model [1]. From the time-activity curves, cumulative activities and residence times of 99m Tc-DTPA in the kidneys, brain, upper large intestine (ULI), small intestine (SI), lower large intestine (LLI), stomach, heart, liver, lung and remainder of the body was calculated. Using the information of residence times of the total body and urinary bladder voiding at 2.4 hours on MIRD 12 absorbed dose for the

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Section: Resultsmentioning

confidence: 98%

Bio-Distribution and Dosimetry of a Renal Agent in Normal Bangladeshi Subjects

et al. 2013

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“…The average dose rate in the tissue from the uniformly incorporated gamma emitters is calculated •"iththe following formula [1][2][3][4][5]: RADIOPROTECTION -COLLOQUES P r =1.1454^-r-g- ; (3) where P Y is the average dose rate, pGy-s" 1 ; y is the activity concentration of a radionuclide in the tissue Bq-kg" 1 ; r is the gamma radiation constant of the radionuclide, aGy-m 2 -(s-Bq)"'; g is the average geometric factor, cm. The values of the average geometric factors for cylinders of different sizes were calculated in the specialized dosimetric literature [1].…”

Section: Methodology For Dose Assessment To Aquatic Biota 21 Radiatiomentioning

confidence: 99%

“…The radionuclide activity concentration y (Bq-kg" 1 of the absorber mass) corresponds to the emitter content m the organism' s tissues. The value of dose rate P" or Pg° (pGy-s" 1 ) can be found using the following formula [1][2][3][4][5]:…”

Section: Methodology For Dose Assessment To Aquatic Biota 21 Radiatiomentioning

confidence: 99%

“…The internal doses to the local biota are the same as for the Kara Sea biota. External exposure from sediments in the Tsivolki Fjord was estimated to be about 110-10" 9 Gy-day" 1 . During the survey to the Abrosimov Fjord [9], small local spots of bottom contamination were found in the vicinity of some dumped containers with radioactive wastes (but not near containers with the spent fuel).…”

Section: Current Dose Levels To Marine Biota Near Rw Disposal In Thmentioning

confidence: 99%

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Assessment of doses for Arctic marine biota

et al. 2002

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Abstract. The objectives of this paper are the presentation of site-specific radioecological information and development of models, which can be used to calculate doses to Arctic marine biota. The methodology of calculating doses from a, P, and y-emitters is presented. This methodology is realized in form of computer code DOSBIO, and model parameters are evaluated. The following annual doses to biota are calculated: internal dose from radionuclides incorporated in the organisms; external dose from contaminated water; external dose from contaminated bottom sediments; total dose as a sum of internal and external doses. Dose conversion factors are calculated for 15 species of marine biota, including fish, sea mammals, molluscs. The list of species includes cod, plaice, haddock, herring, redfish, Greenland halibut, char, saithe, Greenland seal, white whale, ringed seal, bearded seal, and others. The calculations are performed for adult representatives of each species. Calculated dose conversion factors are presented for 11 different radionuclides (H-3, C-14, K-40, Sr-90, Tc-99, Sb-124, Cs-137, Eu-152, Po-210, Pu-239, Am-241). The current and potential doses to marine biota from the Barents and Kara Seas are estimated.

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“…To know the risk of administered radiopharmaceuticals, the measurement of distributed radio activities and the estimation of absorbed dose in the organs are termed as internal dosimetry. [1][2][3][4][5][6] The present time there is an increased interest in evaluating the absorbed dose delivered to patients by radiopharmaceutical. Recently, about 120 radiopharmaceuticals used in nuclear medicine, has been published by ICRP-53 publication.…”

Section: Introductionmentioning

confidence: 99%