2011
DOI: 10.4269/ajtmh.2011.10-0512
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Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine against Malaria and Anemia in Pregnant Women

Abstract: Abstract. The effectiveness of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) against malaria and anemia is unclear because of the spread of SP-resistant Plasmodium falciparum . This study evaluates the effectiveness of IPTp-SP among pregnant women attending the antenatal clinic at Korle-Bu Teaching Hospital in Accra, Ghana. A cross-sectional study comparing malaria and anemia prevalence among pregnant women using IPTp-SP with non-IPTp-SP users was conducted during … Show more

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Cited by 52 publications
(56 citation statements)
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“…We show in this study that, pregnant women who took two doses of SP were not significantly protected against PM, LBW, MA. Preliminary data from previous studies have suggested a continued trend in reduction of effectiveness of SP for IPTp in many African countries 13,37,39 .…”
Section: Discussionmentioning
confidence: 99%
“…We show in this study that, pregnant women who took two doses of SP were not significantly protected against PM, LBW, MA. Preliminary data from previous studies have suggested a continued trend in reduction of effectiveness of SP for IPTp in many African countries 13,37,39 .…”
Section: Discussionmentioning
confidence: 99%
“…There was no statistical difference in the incidence of preterm delivery (P=0.262), cord blood parasitaemia (P=0.385), low birth weight (P=0.175) and birth asphyxia (P=0.367) between the two study groups. So, the authors conclude that there was no significant difference between intermittent preventive treatment with sulphadoxinepyrimethamine and the use of daily proguanil so larger studies with proguanil are warranted 92 . Additionally, another cross sectional study was conducted to evaluate the effectiveness of Intermittent Preventive Treatment with SP among pregnant women attending the antenatal clinic at Korle-Bu Teaching Hospital in Accra, Ghana.…”
Section: Intermittent Anti Malaria Therapymentioning
confidence: 98%
“…The 2011 multiple indicator cluster survey from Ghana indicated progress on IPTp in Ghana although this has not been sustained 11 . IPTp-SP administered to pregnant women in their second and third trimesters has been observed to reduce the risk of malaria 12,13 , placental malaria 8 , low birth weight and preterm births [12][13][14] , and maternal anaemia 13,15 . SP has a good safety profile 16 , and is cheap, cost effective and easy to administer through the already existing antenatal-care clinics (ANC) 10,17 .…”
Section: Introductionmentioning
confidence: 99%