Intermittent hypoxia: Friend and foe

Environment and exposure

“…19 Sleep apnoea is a pathophysiological phenomenon of rising incidences because of, for example, the obesity epidemic, demographic change and a rise in predisposing conditions, characterized by detrimental intermittent hypoxia (reviewed in Ref. 20). In a rodent model of sleep apnoea, Laouafa et al showed a protective role of female sexual hormones against several components of sleep apnoea pathophysiology, including mitochondrial dysfunction, with potential therapeutic implications for menopausal patients.…”

“…Sleep apnoea is a pathophysiological phenomenon of rising incidences because of, for example, the obesity epidemic, demographic change and a rise in predisposing conditions, characterized by detrimental intermittent hypoxia (reviewed in Ref 20…”