Intermittent Fasting Effects on the Central Nervous System: How Hunger Modulates Brain Function

Cerqueira, Fernanda M.; Chausse, Bruno; Kowaltowski, Alicia J.

doi:10.1007/978-3-319-40007-5_29-1

Cited by 2 publications

(1 citation statement)

References 69 publications

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“…It is known that fasting implies several physiological changes to the body, among which is autonomic nervous system function, and thereby the heart rate. 40 Fasting has been shown to affect heart rate in controversial ways among patients with hypertension, where it may leave it unchanged or reduce it significantly. One of the hypothesized mechanisms in lowering heart rate is the stimulation of cholinergic pathways, and hence, the activation of the parasympathetic nervous system.…”

Section: Fasting and Autonomic Nervous Systemmentioning

confidence: 99%

Impact of Fasting on Cardiovascular Outcomes in Patients With Hypertension

Hammoud

Kurdi

Bemt

2021

Journal of Cardiovascular Pharmacology

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Fasting has been frequently practiced for religious or medical purposes worldwide. However, limited literature assesses the impact of different fasting patterns on the physiologic and cardiac-related parameters in patients with hypertension. This review aims to examine the effect of fasting on cardiovascular outcomes in hypertensive patients. Medline, Embase, and Cochrane library were systematically screened until March 2021 for observational prospective cohorts investigating the effect of fasting on cardiovascular outcomes. Articles were assessed by searching for hypertension and fasting, both as Medical Subject Headings (MeSH) terms and text words. The review included studies assessing Ramadan, intermittent, and water-only fasting. Water-only fasting reduces body weight, blood pressure, and lipolytic activity of fasting hypertensive patients without affecting average heart rate. Ramadan fasting enhances lipid profile, although it shows conflicting results for body weight, blood pressure, and heart rate variability. Considering the limited studies in this field, further research should be conducted to support the clinical impact of fasting on the cardiovascular health of patients with hypertension.

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Section: Fasting and Autonomic Nervous Systemmentioning

confidence: 99%

Impact of Fasting on Cardiovascular Outcomes in Patients With Hypertension

Hammoud

Kurdi

Bemt

2021

Journal of Cardiovascular Pharmacology

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Intermittent Fasting: Is the Wait Worth the Weight?

2018

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Numerous variations of IF exist, and study protocols vary greatly in their interpretations of this weight loss trend. Most human IF studies result in minimal weight loss and marginal improvements in metabolic biomarkers, though outcomes vary. Some animal models have found that IF reduces oxidative stress, improves cognition, and delays aging. Additionally, IF has anti-inflammatory effects, promotes autophagy, and benefits the gut microbiome. The benefit-to-harm ratio varies by model, IF protocol, age at initiation, and duration. We provide an integrated perspective on potential benefits of IF as well as key areas for future investigation. In clinical trials, caloric restriction and IF result in similar degrees of weight loss and improvement in insulin sensitivity. Although these data suggest that IF may be a promising weight loss method, IF trials have been of moderate sample size and limited duration. More rigorous research is needed.

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Intermittent Fasting Effects on the Central Nervous System: How Hunger Modulates Brain Function

Cited by 2 publications

References 69 publications

Impact of Fasting on Cardiovascular Outcomes in Patients With Hypertension

Impact of Fasting on Cardiovascular Outcomes in Patients With Hypertension

Intermittent Fasting: Is the Wait Worth the Weight?

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