Intermediate Uveitis and Sarcoidosis

Graham, Elizabeth; Edelsten, Clive

doi:10.1159/000429636

Cited by 12 publications

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“…In our series, only 2.3% of the cases were associated with multiple sclerosis. The relatively lower frequency of multiple sclerosis in our series compared to those found in previous reports [20, 22,25] may be related to genetic and environmental factors.…”

Section: Discussioncontrasting

confidence: 78%

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Clinical characteristics of intermediate uveitis in Tunisian patients

et al. 2010

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To analyze the pattern of intermediate uveitis (IU) in a referral center in Tunisia, North Africa. A retrospective, descriptive study of 87 consecutive patients (145 eyes) examined at the Department of Ophthalmology of Monastir (Tunisia) from January 1996 to August 2008. All patients underwent an extensive ocular and systemic history, a complete ophthalmic examination, and fluorescein angiography. Standard diagnostic criteria of IU were employed. The mean follow-up period was 43.2 months (range, 4-65 months). The mean age at diagnosis of IU was 29.1 years (range, 5-54 years). The male-to-female ratio was 1:1.6. Both eyes were affected in 58 patients (66.7%). The best-corrected visual acuity at onset of uveitis ranged from light perception to 20/20 (mean, 20/32). The most frequent ocular findings were vitritis (100%), snowballs (53.8%), and retinal vasculitis (28.3%). Concurrent anterior uveitis was noted in 38.6% of affected eyes. Intermediate uveitis was most commonly idiopathic (86.2%). Systemic associations were found in 13.8%; sarcoidosis (9.2%) and multiple sclerosis (2.3%) were the most common systemic diseases. The ocular complications that developed during the follow-up period included cystoid macular edema (39.3%), cataract (31.7%), inflammatory optic disc involvement (26.2%), and glaucoma or ocular hypertension (9%). One hundred-twelve affected eyes (77.2%) had a final visual acuity more than or equal to 20/40. Factors of poor visual outcome were initial VA less than 20/40 (P = 0.00011), CME (P = 0.0016), and vitritis more than 3+ cells (P = 0.023). In a hospital population in Tunisia, intermediate uveitis started frequently at the 3rd decade. This type of uveitis was most commonly idiopathic. Cystoid macular edema and cataract were the most frequent complications. Visual prognosis appeared to be fairly good.

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Section: Discussioncontrasting

confidence: 78%

“…The most common specific diagnoses in our series were sarcoidosis and 22,23]; nevertheless they were not observed in our series. The association between multiple sclerosis and IU is well documented [24,25].…”

Section: Discussioncontrasting

confidence: 78%

Clinical characteristics of intermediate uveitis in Tunisian patients

et al. 2010

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“…This disease has been reported in more than one member of a family [11]; in our study, there were two male cousins. The most common systemic associations are multiple sclerosis [5,12] and sarcoidosis [ 13]; but we found neither these nor any other systemic diseases.…”

Section: Discussioncontrasting

confidence: 78%

Pars planitis: epidemiology and clinical outcome in a large community hospital in Mexico city

Ortega-Larrocea

Arellanes-García

1995

Int Ophthalmol

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Medical records of 51 patients with a diagnosis of pars planitis (97 eyes) were reviewed. Based upon the severity of vitreous inflammation, in 34 eyes (35%) the condition was classified as mild, in 38 (39%) as moderate, and in 25 eyes (26%) as severe. Vascular sheathing was present in 51 eyes (53%), snowballs in 42 (43%), snowbanks in 29 (30%), cataract in 19 (20%), cystoid macular edema in 26 (27%), retinal detachment in 4 (4%) and glaucoma in 3 (3%) eyes. Treatment consisted of prednisone and periocular injections of deposteroids or immunosuppressive agents; 13 patients required surgery for retinal repair, glaucoma, vitreous opacities or cataract. After treatment the visual acuity improved in 58% of the eyes, did not change in 33%, and worsened in 9%.

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“…4,9,16 Bu çalışmada pars planit ve idyopatik İÜ'lerin toplam oranı %60 olarak saptanmıştır. İÜ'lerin en sık nedeni genellikle sarkoidozdur, 17,18,19 bu çalışmalarda genellikle %10'un üzerindedir. Bizim çalışmamızda da en sık etyolojik hastalık multiple skleroz (%22,9) ve sarkoidozdur (%11,4).…”

Section: Discussionunclassified

Clinical Characteristics of Patients with Intermediate Uveitis

Güngör¹,

Akova²

2014

tjo

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Amaç: İntermediyer üveit tanılı hastaların klinik özelliklerinin ve bulgularının incelenmesi. Gereç ve Yöntem: 1996-2011 yılları arasında kliniğimizde intermediyer üveit tanısı konulan 35 hastanın kayıtları retrospektif olarak incelendi. Hastaların düzeltilmiş görme keskinliği, göz içi basınç ölçümü, biyomikroskopik ön segment muayene bulguları, dilate fundus muayenesi, fundus floresein anjiyografi bulguları ve sistemik muayene sonuçları kaydedildi. Bulgular: Ortalama takip süresi 6,2 yıldı (2-16 yıl). Ortalama tanı konulma yaşı 32,4 yıldı (8-68 yıl). Hastaların %17,1'i 18 yaş altındaydı. Hastaların %65,7'si kadın, %34,2'si erkekti ve % 54,3'ünün iki gözü de etkilenmişti. En sık görülen bulgular vitrit (%100), kartopu opasite (%97,1), retinal vaskülit (%65,7) ve kar birikintisi görünümüydü (%45,7). Hastaların % 71,4'ünde iridosiklit eşlik etmekteydi. % 40,1 hastada eşlik eden sistemik hastalık tespit edildi, bu hastalıklar sırasıyla multiple skleroz (%22,9), sarkoidoz (%11,4), tüberküloz (%2,9) ve Lyme hastalığıydı (%2,9). Takip süresince gelişen en sık komplikasyonlar sekonder glokom (%22,9), katarakt (%17,1) ve kistoid maküler ödemdi (%17,1). Bir hastada optik atrofi, bir hastada maküler delik ve bir hastada kistoid maküler ödem sekeline bağlı görme keskinliği 0,5'in altında kaldı. Geri kalan hastaların son görme keskinliği ortalama 0,9±0,2'di. Sonuç: İntermediyer üveitte inflamasyon ve komplikasyonlar etkin tedavi edilirse görme prognozu oldukça iyidir. Detaylı klinik değerlendirmeyle olguların bir kısmında sistemik hastalık başlangıçta veya daha sonraki takiplerde saptanabilir. (Turk J Ophthalmol 2014; 44: 27-30) Anahtar Kelimeler: İntermediyer üveit, pars planit, klinik bulgular, epidemiyoloji Özet Objectives: To analyze the clinical characteristics and findings in patients with intermediate uveitis. Materials and Methods: The records of the 35 patients diagnosed as intermediate uveitis in our clinic between years 1996 and 2011 were reviewed retrospectively. Best-corrected visual acuity, intraocular pressure, slit lamp examination, dilated fundus examination, fundus fluorescein angiography, and systemic examination results of the patients were noted. Results: The mean follow-up time was 6.2 years (2-16 years). The mean age at diagnosis of intermediate uveitis was 32.4 years (8-68 years). 17.1% of patients were under 18 years old. 65.7% of patients were women, 34.2% were men, and both eyes were affected in 54.3% of patients. The most frequent findings were vitritis (100%), snowball opacities (97.1%), retinal vasculitis (65.7%), and snowbanking (45.7%). Concurrent iridocyclitis was determined in 71.4% of patients. Systemic association was found in 40.1% of patients, with disease being multiple sclerosis (22.9%), sarcoidosis (11.4%), tuberculosis (2.9%), or Lyme disease (2.9%). The most common complication that developed during the follow-up period included secondary glaucoma (22.9%), cataract formation (17.1%), and cystoid macular edema (17.1%). The visual acuity of 3 patients was less than 0.5 due to the opti...

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Intermediate Uveitis and Sarcoidosis

Cited by 12 publications

References 0 publications

Clinical characteristics of intermediate uveitis in Tunisian patients

Clinical characteristics of intermediate uveitis in Tunisian patients

Pars planitis: epidemiology and clinical outcome in a large community hospital in Mexico city

Clinical Characteristics of Patients with Intermediate Uveitis

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