Intermediate Survival and Predictors of Death After Surgical Ventricular Restoration

Donato, Marisa Di; Toso, Anna; Maioli, Mauro; Sabatier, M.; Stanley, Alfred W.H.; Dor, Vincent

doi:10.1053/stcs.2001.29972

Cited by 107 publications

(67 citation statements)

References 17 publications

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“…Despite early reports of high mortality with this technique, recent studies indicate a hospital mortality of Ͻ7% in patients with end stage ICM. [1][2][3][4] In our previous studies, we demonstrated that LV reconstruction surgery combined with coronary revascularization for patients with ICM could significantly reduce symptoms in patients refractory to medical therapy and that an LV end-diastolic volume Ͻ150 mL after surgery predicted a favorable short term outcome. 3,5 In contrast, persistent mitral regurgitation (MR) was found to be a strong predictor of poor long-term prognosis.…”

mentioning

confidence: 99%

Importance of Mitral Valve Repair Associated With Left Ventricular Reconstruction for Patients With Ischemic Cardiomyopathy: A Real-Time Three-Dimensional Echocardiographic Study

et al. 2003

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Background-Left ventricular (LV) reconstruction surgery leads to early improvement in LV function in ischemic cardiomyopathy (ICM) patients. This study was designed to evaluate the impact of mitral valve (MV) repair associated with LV reconstruction on LV function 1-year after surgery in ICM patients assessed by real-time 3-dimensional echocardiography (3DE). Methods and Results-Sixty ICM patients who underwent the combination surgery (LV reconstruction in 60, MV repair in 30, and revascularization in 52 patients) were studied. Real-time 3DE was performed and LV volumes were obtained at baseline, discharge, 6-month and Ն12-month follow-up. Reduction in end-diastolic volumes (EDV) by 29% and in end-systolic volumes by 38% were demonstrated immediately after surgery and remained at subsequent follow-up (PϽ0.0001). The LV ejection fraction significantly increased by about 10% at discharge and was maintained Ն12-month (PϽ0.0001). Although the LV volumes were significantly larger in patients with MV repair before surgery (EDV, 235Ϯ87 mL versus 193Ϯ67 mL, PϽ0.05), they were similar to LV volumes of the patients without MV repair at subsequent follow-ups. However, the EDV increased from 139Ϯ24 mL to 227Ϯ79 mL (PϽ0.01) in 7 patients with recurrent mitral regurgitation (MR). Improvement in New York Heart Association functional class occurred in 81% patients during late follow-up. Conclusion-Real-time 3DE demonstrates that LV reconstruction provides significant reduction in LV volumes and improvement in LV function which is sustained throughout the 1-year follow-up with 84% cardiac event free survival. If successful, MV repair may prevent LV redilation, while recurrent MR is associated with increased LV volumes.

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confidence: 99%

Importance of Mitral Valve Repair Associated With Left Ventricular Reconstruction for Patients With Ischemic Cardiomyopathy: A Real-Time Three-Dimensional Echocardiographic Study

et al. 2003

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“…22) Additionally, LV dilatation showed the correlation between increased LV volumes after myocardial infarction with increased mortality. These findings were subsequently reconfirmed by Di Donato, et al and by Dor, et al 11,12) In 2013, Liu and associates studied the patients who underwent either isolated CABG or CABG/ SVR into two different groups according to the pre-operative LVESVI. 23) In their report, the effective revascularization is most …”

Section: Discussionmentioning

confidence: 64%

“…Since pre-operative LVESVI (>100 ml/m 2 ) was demonstrated to be an independent predictor of long-term mortality following isolated CABG, SVR has been concomitantly performed in patients with a dilated LV due to ICM. 4,11) According to these reports, we have been performing SVR in patients with ICM and large LVESVI (>100 ml/m 2 ). Dor and associates documented that cardiac geometric and functional data such as LV end-diastolic volume index (LVEDVI), LVESVI and EF were improved at early and 1 year after the operation.…”

Section: Discussionmentioning

confidence: 99%

Strategy of Treatment for Ischemic Cardiomyopathy

et al. 2013

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“…21,22 In a study of 48 patients with EF <0.3 and LVESVI <100 ml/m 2 , Cox's proportional hazards model identified LVR and renal failure as independent factors that affected actuarial survival with odds ratios of 0.28 and 3.64, respectively (P<0.05). The 5-year actuarial survival (Kaplan-Meier) was significantly greater following LVR (90±11%) compared with isolated CABG (53±17%).…”

Section: Left Ventricular (Lv) Restoration and Ischemic Cardiomyopathmentioning

confidence: 99%

Surgical Treatment for Heart Failure

Isomura

2009

Circ J

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Congestive heart failure has become a major problem and the only surgical treatment for end-stage heart failure caused by dilated cardiomyopathy (DCM) had been heart transplantation. However, because of the shortage of donors, several procedures for non-transplant surgery have been developed. Published literature on left ventricular (LV) restoration was searched to review the new surgical procedures for treating patients with ischemic or non-ischemic DCM. LV restoration was initiated in the 1980s for repairing LV aneurysm. In the 1990s several surgical procedures were introduced for treating DCM, and the new evolving surgical treatment plays an important role in the management of DCM in the 21st century. (Circ J 2009; Suppl A: A-6 -A-12)

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Intermediate Survival and Predictors of Death After Surgical Ventricular Restoration

Cited by 107 publications

References 17 publications

Importance of Mitral Valve Repair Associated With Left Ventricular Reconstruction for Patients With Ischemic Cardiomyopathy: A Real-Time Three-Dimensional Echocardiographic Study

Importance of Mitral Valve Repair Associated With Left Ventricular Reconstruction for Patients With Ischemic Cardiomyopathy: A Real-Time Three-Dimensional Echocardiographic Study

Strategy of Treatment for Ischemic Cardiomyopathy

Surgical Treatment for Heart Failure

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