Intermediate metabolism during the ontogenetic development of Anastrepha fraterculus (Diptera: Tephritidae)

Dutra, Bibiana Kaiser; Fernandes, Felipe Amorim; Nascimento, Jurema Cruz do; Quadros, Felipe C.; Oliveira, Guendalina Turcato

doi:10.1016/j.cbpa.2006.08.033

Cited by 8 publications

(5 citation statements)

References 19 publications

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“…A general role of AKH in this process has been predicted based on, e.g., experimental evidence that AKH injections cause differential glycogen or lipid mobilization in a developmental stage-specific manner in Manduca sexta (Gäde and Beenakkers 1977) or Zophobas atratus (Slocinska et al 2013;Gołębiowski et al 2014). Preference for lipids or glycogen as energy sources and dynamics of their usage during metamorphosis vary considerably among species (Nestel et al 2003;Dutra et al 2007). Similarly, as recently described by Matsuda et al (2015), we also noticed that metamorphosis of Drosophila is fueled to a considerable extent by glycogen, but lipids are mobilized as well.…”

Section: Developmental Roles Of Akh Signalingsupporting

confidence: 82%

Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants

et al. 2015

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Maintenance of biological functions under negative energy balance depends on mobilization of storage lipids and carbohydrates in animals. In mammals, glucagon and glucocorticoid signaling mobilizes energy reserves, whereas adipokinetic hormones (AKHs) play a homologous role in insects. Numerous studies based on AKH injections and correlative studies in a broad range of insect species established the view that AKH acts as master regulator of energy mobilization during development, reproduction, and stress. In contrast to AKH, the second peptide, which is processed from the Akh encoded prohormone [termed "adipokinetic hormone precursor-related peptide" (APRP)] is functionally orphan. APRP is discussed as ecdysiotropic hormone or as scaffold peptide during AKH prohormone processing. However, as in the case of AKH, final evidence for APRP functions requires genetic mutant analysis. Here we employed CRISPR/Cas9-mediated genome engineering to create AKH and AKH plus APRP-specific mutants in the model insect Drosophila melanogaster. Lack of APRP did not affect any of the tested steroid-dependent processes. Similarly, Drosophila AKH signaling is dispensable for ontogenesis, locomotion, oogenesis, and homeostasis of lipid or carbohydrate storage until up to the end of metamorphosis. During adulthood, however, AKH regulates body fat content and the hemolymph sugar level as well as nutritional and oxidative stress responses. Finally, we provide evidence for a negative autoregulatory loop in Akh gene regulation.KEYWORDS Drosophila; adipokinetic hormone; adipokinetic hormone precursor-related peptide; energy homeostasis; stress resistance E NERGY homeostasis requires continuous compensation for fluctuations in the energy expenditure and availability of food resources. Organisms thus build up reserves under positive energy balance and catabolize them when the balance turns negative to retain stable levels of circulating energy fuel. Insulin signaling induces the uptake of excessive circulating sugars, thus promoting reserve accumulation (reviewed, e.g., in Saltiel and Kahn 2001; Cohen 2006), whereas energy mobilization is under the control of glucagon and glucocorticoid signaling in mammals (reviewed, e.g., in Rui 2014;Charron and Vuguin 2015) and adipokinetic hormone (AKH) signaling in insects (reviewed, e.g., in Van der Horst 2003;Lorenz and Gäde 2009;Bednářová et al. 2013a). Consistent with their fundamental physiological function in energy mobilization, AKHs are found not only in insects, but are common in Protostomia, where they have been identified both in Ecdyszoa (in Arthropoda, Tardigrada, and Priapulida) and Lophotrochozoa (in Mollusca, Rotifera, and Annelida) (Gäde 2009;Hauser and Grimmelikhuijzen 2014). Nevertheless, physiological functions of AKHs have been studied mainly in Arthropoda. Similar to mammals, also insects store lipids in the form of triacylglycerides (TGs) and as carbohydrates in the form of glycogen. The main storage organ for lipid and glycogen in insects is the fat body, which can thus b...

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Section: Developmental Roles Of Akh Signalingsupporting

confidence: 82%

Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants

et al. 2015

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“…during the same period in field conditions); nevertheless, variations are so large that they must be representative of physiological changes associated to summer metamorphosis. The loss of dry weight found between spring larvae and adult females entering diapause is consistent with a high level of metabolism and with costly physiological changes linked to metamorphosis of holometabolous insects ( Nestel et al , 2003;Wang et al , 2006;Dutra et al , 2007 ). Surprisingly, however, lipids drastically increase from larvae to adult females, by more than 31% of their initial absolute amount (65% if corrected by mg dry weight).…”

Section: Discussionsupporting

confidence: 70%

“…This suggests that teneral lipids may have a predominant role for adult active life in C. nucum . Lipids of larval origin stored in emerging adults are positively related to fitness components ( Ellers and Van Alphen, 2002;Dutra et al , 2007;Hahn & Denlinger, 2007 ). Hence, lipid concentration could be fixed upon adult emergence.…”

Section: Discussionmentioning

confidence: 99%

Ecophysiological attributes of adult overwintering in insects: insights from a field study of the nut weevil, Curculio nucum

Bel‐Venner

Mondy

Arthaud

et al. 2009

Physiological Entomology

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International audienceDiapausing insect species have evolved a great diversity of life cycles, although overwintering occurs at a single development stage within most species. Understanding why diapause has evolved towards a given life stage requires investigation of both the ecological and physiological attributes. Notably, it is suggested that adult overwintering is more energy-demanding than larval overwintering but it brings fitness gains by allowing adults to be synchronized with their seasonal requisites through an early spring emergence. This hypothesis is tested in field conditions in the nut weevil Curculio nucum , whose life cycle comprises an obligate 2-year, nonfeeding underground phase, including a larval, followed by an adult, overwintering. In this species, adult wintering leads to an early spring emergence; at first glance, however, this does not enhance synchronization between weevils and their host because adults emerge more than 1 month before starting to breed. It is suggested that adult overwintering ultimately evolved in response to the phenology of the host, by allowing females to oviposit in nuts before their full sclerotinization. Adult overwintering appears to be costly because adults postpone reproduction for 1 year, incur a significant weight loss and require feeding before egg laying. Surprisingly, lipids are unaffected during diapause, lipogenesis even being likely in the summer metamorphosis. These results suggest that the lipids involved in egg production may entirely come from the larval stages, whereas the other nutrients are acquired through adult feeding but this remains to be tested

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“…The nominal species Anastrepha fraterculus represents a cryptic species complex (Stone, 1942; Malavasi & Morgante, 1982; Steck, 1991; Selivon & Perondini, 1998; Hernández-Ortiz et al ., 2004; Selivon et al ., 2004; Selivon et al ., 2005; Vera et al ., 2006; Hernández-Ortiz et al ., 2012, 2015; Canal et al ., 2015; Manni et al ., 2015) that shows pre- and post-zygotic reproductive incompatibilities among lineages (Selivon et al ., 1999; Vera et al ., 2006; Cáceres et al ., 2009; Segura et al ., 2011; Rull et al ., 2013; Devescovi et al ., 2014; Vaníčková et al ., 2015a). This species, known as the South American fruit fly, is a polyphagous species considered the most important native pest of native and commercial fruits in South America (Dutra et al ., 2007; Alberti et al ., 2008). It is widely distributed from northern Mexico to the south of South America (Stone, 1942; Aluja, 1994; Hernández-Ortiz et al ., 2015) and infests more than 116 hosts (Zucchi, 2016).…”

Section: Introductionmentioning

confidence: 99%

Pheromone emission patterns and courtship sequences across distinct populations withinAnastrepha fraterculus(Diptera-Tephritidae) cryptic species complex

Roriz

Japyassú

Cáceres³

et al. 2018

Bull. Entomol. Res.

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Sexual behavioural isolation can result from sexual selection and represents a relevant factor associated with the speciation process. We analysed the pheromone emission pattern and the courtship of males of five different populations of the Anastrepha fraterculus cryptic complex: Brazil (Vacaria, Tucumán and Piracicaba), Colombia and Peru. The time of pheromone emission was recorded in each population every 30 min during the day. The behavioural sequences of courting were video recorded and analysed using EthoSeq software. Males from different populations have showed different period of pheromone emission – Vacaria, Piracicaba and Tucumán executed calling only during the morning, Colombia only in the afternoon and Peru during both periods. The general frequencies of the courtship units of the males were distinct among the populations. Three groups were formed in the classification from the function of 14 behavioural routines: Vacaria, Piracicaba and Tucumán formed a single group (Brazil-1), while Colombia and Peru formed two distinct groups. In the probabilistic trees generated, the behavioural units that most contributed to the occurrence of copulation were distinct among the three groups formed: Brazil-1 (Contact, Alignment and Arrowhead-1); Colombia (Flying, Mobile, Contact and Alignment); Peru (Flying, Arrowhead-1 and Calling). Our results indicated differences in sexual behaviour that may explain the behavioural isolation found between the distinct groups in addition with the temporal isolation found between the Brazil-1 and Colombia populations. The evolutionary implications for the A. fraterculus cryptic species complex are discussed.

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Intermediate metabolism during the ontogenetic development of Anastrepha fraterculus (Diptera: Tephritidae)

Cited by 8 publications

References 19 publications

Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants

Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants

Ecophysiological attributes of adult overwintering in insects: insights from a field study of the nut weevil, Curculio nucum

Pheromone emission patterns and courtship sequences across distinct populations withinAnastrepha fraterculus(Diptera-Tephritidae) cryptic species complex

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