Intermediate- and long-term associations between air pollution and ambient temperature and glycated hemoglobin levels in women of child bearing age

He, Mike Z.; Kloog, Itai; Just, Allan C.; Gutiérrez-Ávila, Iván; Colicino, Elena; Téllez-Rojo, Martha M; Pizano-Zárate, María Luisa; Tamayo‐Ortiz, Marcela; Cantoral, Alejandra; Soria-Contreras, Diana C.; Baccarelli, Andrea A.; Wright, Robert O.; Yitshak‐Sade, Maayan

doi:10.1016/j.envint.2022.107298

Cited by 5 publications

(1 citation statement)

References 58 publications

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“…We also found that postpartum exposure to PM 2.5 was linked to fasting glucose metabolism, with a stronger adverse effect for women with GDM. A Mexican cohort found that 3 month and 6 month PM 2.5 exposure was associated with increased glycated hemoglobin at 4, 6, and 8 years postpartum. Based on the Taiwan Birth Certificate Database, a retrospective cohort study also reported a higher risk of type 2 diabetes related to postpartum PM 2.5 exposure, with an enhanced risk among those with GDM .…”

Section: Discussionmentioning

confidence: 99%

Gestational and Postpartum Exposure to PM_2.5 Components and Glucose Metabolism in Chinese Women: A Prospective Cohort Study

Chen,

Wang,

Chen

et al. 2024

Environ. Sci. Technol.

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Pregnant women are physiologically prone to glucose intolerance, while the puerperium represents a critical phase for recovery. However, how air pollution disrupts glucose homeostasis during the gestational and early postpartum periods remains unclear. This prospective cohort study conducted an oral glucose tolerance test and measured the insulin levels of 834 pregnant women in Guangzhou, with a follow-up for 443 puerperae at 6−8 weeks postpartum. Residential PM 2.5 and five chemical components were estimated by an established spatiotemporal model. The adjusted linear model showed that an IQR increase in gestational PM 2.5 exposure was associated with an increase of 0.17 mmol/L (95% CI: 0.06, 0.28) in fasting plasma glucose (FPG) and 0.24 (95% CI: 0.05, 0.42) in the insulin resistance index. Postpartum PM 2.5 exposure was linked to a 0.17 mmol/L (95% CI: 0.05, 0.28) elevation in FPG per IQR, with a strengthened association found in women with gestational diabetes (P interaction = 0.003). In the quantile-based g-computation model, NO 3 − consistently contributed to the combined effect of PM 2.5 components on gestational and postpartum FPG. This study was the first to suggest that PM 2.5 components were associated with exacerbated gestational insulin resistance and elevated postpartum FPG. Targeted interventions reducing the emissions of toxic PM 2.5 components are essential to improving maternal glucose metabolism.

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Section: Discussionmentioning

confidence: 99%

Gestational and Postpartum Exposure to PM_2.5 Components and Glucose Metabolism in Chinese Women: A Prospective Cohort Study

Chen,

Wang,

Chen

et al. 2024

Environ. Sci. Technol.

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The impact of daily mean air temperature on the proportion of time in hypoglycemia in 2,582 children and adolescents with type 1 diabetes – Is this association clinically relevant?

Lanzinger

Biester

Siegel

et al. 2023

Environmental Research

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Associations between air pollution, residential greenness, and glycated hemoglobin (HbA1c) in three prospective cohorts of U.S. adults

Fiffer,

Li,

Iyer

et al. 2023

Environmental Research

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Intermediate- and long-term associations between air pollution and ambient temperature and glycated hemoglobin levels in women of child bearing age

Cited by 5 publications

References 58 publications

Gestational and Postpartum Exposure to PM_2.5 Components and Glucose Metabolism in Chinese Women: A Prospective Cohort Study

Gestational and Postpartum Exposure to PM_2.5 Components and Glucose Metabolism in Chinese Women: A Prospective Cohort Study

The impact of daily mean air temperature on the proportion of time in hypoglycemia in 2,582 children and adolescents with type 1 diabetes – Is this association clinically relevant?

Associations between air pollution, residential greenness, and glycated hemoglobin (HbA1c) in three prospective cohorts of U.S. adults

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Intermediate- and long-term associations between air pollution and ambient temperature and glycated hemoglobin levels in women of child bearing age

Cited by 5 publications

References 58 publications

Gestational and Postpartum Exposure to PM2.5 Components and Glucose Metabolism in Chinese Women: A Prospective Cohort Study

Gestational and Postpartum Exposure to PM2.5 Components and Glucose Metabolism in Chinese Women: A Prospective Cohort Study

The impact of daily mean air temperature on the proportion of time in hypoglycemia in 2,582 children and adolescents with type 1 diabetes – Is this association clinically relevant?

Associations between air pollution, residential greenness, and glycated hemoglobin (HbA1c) in three prospective cohorts of U.S. adults

Contact Info

Product

Resources

About

Gestational and Postpartum Exposure to PM_2.5 Components and Glucose Metabolism in Chinese Women: A Prospective Cohort Study

Gestational and Postpartum Exposure to PM_2.5 Components and Glucose Metabolism in Chinese Women: A Prospective Cohort Study