Interligand interactions involved in the molecular recognition between copper(II) complexes and adenine or related purines

Choquesillo-Lazarte, Duane; Brandi-Blanco, María del Pilar; García‐Santos, Isabel; González‐Pérez, Josefa María; Castiñeiras, Alfonso; Niclós‐Gutiérrez, Juan

doi:10.1016/j.ccr.2007.09.018

Cited by 71 publications

(40 citation statements)

References 57 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[11] Adenine is known to establish various molecular recognition patterns with molecules that are compatible with its hydrogen-bonding scheme. [12] In this way, the inclusion of additional species within the structure of adenine-containing dinuclear entities provides a better understanding of the preponderance of these hydrogen-bonding patterns.…”

Section: Introductionmentioning

confidence: 99%

Supramolecular Architectures and Magnetic Properties of Self‐Assembled Windmill‐Like Dinuclear Copper(II) Complexes with Purine Ligands

et al. 2009

View full text Add to dashboard Cite

O (3) [in which ade = adeninate anion, Hade = 7H-adenine, 6Clpur = 6-chloropurinate anion, bpa = 1,2-bis(4-pyridyl)ethane, pic = 2-pyridinecarboxylate anion], are reported. Their crystal structures consist of dinuclear copper(II) units, in which four ligands arranged in a windmill-like fashion bridge the metal ions through a nonlinear NCN group. Supramolecular crystal building of compound 1 is essentially maintained by an extensive network of hydrogen-bonding interactions that involves direct contacts between the nucleobases. In contrast, in compound 2 there is no evidence for direct interactions between the nucleobases, but the hydrogen bonds among the nucleobases and nitrate counteranions are especially relevant. Compound 3 is mainly built up from T-shaped noncovalent Cl···N inter-

show abstract

Section: Introductionmentioning

confidence: 99%

Supramolecular Architectures and Magnetic Properties of Self‐Assembled Windmill‐Like Dinuclear Copper(II) Complexes with Purine Ligands

et al. 2009

View full text Add to dashboard Cite

show abstract

“…The field of nucleic acid-metal ion interactions is very broad, with multidisciplinary contributions that go beyond the perspectives of traditional areas of science such as biology, biochemistry, genetics, and medicinal chemistry, among others [8].…”

Section: Introductionmentioning

confidence: 99%

Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper(II) complex with N-(9H-purin-6-yl)benzenesulfonamide and 1,10-phenantroline. Antitumor activity in human Caco-2 cells and Jurkat T lymphocytes. Evaluation of p53 and Bcl-2 proteins in the apoptotic mechanism

García-Giménez

González‐Álvarez

Liu‐González

et al. 2009

Journal of Inorganic Biochemistry

205

View full text Add to dashboard Cite

“…Stereospecifi c interligand interactions, involving hydrogen bonding, electrostatic repulsions, or steric constraints, are important factors that affect nucleobase and site-specifi c metal bonding [68][69][70] . For example, in the tripodal tetradentate nta ligand (nta = nitrilotriacetate) system [69a], where nta bears three carboxylate groups that could function as hydrogen bonding acceptors only, the nta-capped octahedral metal ion binds exclusively to adenine at N7 over N9-substituted guanine, cytosine, or uracil; this could be due to the formation of the interligand N6-H···O(nta) hydrogen bonding for adenine.…”

Section: Factors Affecting Metal Binding Sitesmentioning

confidence: 99%

Nucleic Acid-Metal Ion Interactions in the Solid State

Aoki

Murayama

2011

Metal Ions in Life Sciences

View full text Add to dashboard Cite

Metal ions play a key role in nucleic acid structure and activity. Elucidation of the rules that govern the binding of metal ions is therefore an essential step for better understanding of the nucleic acid functions. This review is as an update to a preceding one (Metal Ions Biol. Syst., 1996, 32, 91-134), in which we offered a general view of metal ion interactions with mono-, di-, tri-, and oligonucleotides in the solid state, based on their crystal structures reported before 1994. In this chapter, we survey all the crystal structures of metal ion complexes with nucleotides involving oligonucleotides reported after 1994 and we have tried to uncover new characteristic metal bonding patterns for mononucleotides and oligonucleotides with A-RNA and A/B/Z-DNA fragments that form duplexes. We do not cover quadruplexes, duplexes with metal-mediated base-pairs, tRNAs, rRNAs in ribosome, ribozymes, and nucleic acid-drug and -protein complexes. Factors that affect metal binding to mononucleotides and oligonucleotide duplexes are also dealt with.

show abstract

Interligand interactions involved in the molecular recognition between copper(II) complexes and adenine or related purines

Cited by 71 publications

References 57 publications

Supramolecular Architectures and Magnetic Properties of Self‐Assembled Windmill‐Like Dinuclear Copper(II) Complexes with Purine Ligands

Supramolecular Architectures and Magnetic Properties of Self‐Assembled Windmill‐Like Dinuclear Copper(II) Complexes with Purine Ligands

Nucleic Acid-Metal Ion Interactions in the Solid State

Contact Info

Product

Resources

About