Interleukins and metalloproteinases in the lungs of mice with BCG-granulomatosis with the injection of the liposomal form of dextrazide
A.M. Sinyavskaya,
A.V. Troitskii,
T.N. Bystrova
et al.
Abstract:Introduction. An actual decision of the issue of safety and effective drug therapy improvement is the development of transport systems that allow to provide targeted delivery of drugs to target cells, while reducing their toxic effects. The aim of the work was to carry out a comparative study of the effects of isoniazid, composition of isoniazid with oxidized dextran (dextrazid), and liposomal form of dextrazid (LFD) on the levels of interleukins IL-6 and tumor necrosis factor-α (TNF-α), metalloproteinases MMP… Show more
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