“…Earlier observations on the increased serum level of IL-1Ra in SLE patients are convincing, but their relations to the disease activity show contradictions [7,16,23,24]. According to our present results, there is a rather high, significant and concomitant elevation in the serum levels of both IL-1Ra and CRP, and these increases correlate significantly in all groups of SLE patients, but there was a correlation with SLEDAI only in ILN patients.…”