Interleukin-8 stimulating activity of low molecular weight β-glucan depolymerized by γ-irradiation

Effect of γ -irradiation on antioxidant and antiproliferative properties of oat β -glucan

“…Generally biological activities of polysaccharide depend on the molecular structure which includes molar mass, degree of branching and branch length (Qi et al, 2005). Problems with high molecular weight β-glucan are its high viscosity resulting in low permeability into cell and to counter these problems many degradation methods are being used (Methacanon et al, 2011). Previously we reported Gammairradiation leads to the fragmentation of polysaccharide by breaking of glycosidic bonds (Gani et al, 2012).…”

Effect of γ-irradiation on structure and nutraceutical potential of β-d-glucan from barley (Hordeum vulgare)

“…In general, the biological activities of polysaccharides are considered to depend on the molecular structure, including molar mass, degree of branching and length of branch [8]. Problems with high molecular weight ␤-dglucan are its high viscosity and low permeability into cell and to counter these problems many degradation methods are being used [9]. Chemical treatment is an easy, low cost process, but chemical waste and reproducibility are the main problems.…”

Effect of biopolymers on the characteristics and cytocompatibility of biocomposite nanofibrous scaffolds

“…24 These two characteristic peaks diminished with reducing gelatin content, disappearing in the PHGL703 nanofiber, but an additional characteristic shoulder peak was observed at 1080 cm À1 and ascribed to the typical b-glycosidic bonds of laminarin. 25,26 In addition, a characteristic peak centered at 1727 cm À1 was also observed in all samples, which was derived from the C ¼ O stretching of ester groups present in the molecular chain of highly ordered crystalline PHBV. 27 The surface chemical composition of the biocomposite nanofibrous scaffolds was determined by XPS.…”