“…We report a strong induction of numerous pro-inflammatory cytokines, chemokines and AMPs such as CXCL1, CXCL2, CXCL5, CXCL8, CCL20, TNFα, TSLP, IL-23α, IL-32, IL-6, hBD2 and S100A7 during the infection of monolayered primary keratinocytes and reconstructed epidermis with the wild-type PAK strain. Some of these mediators have previously been described during lung [18,24,26–29] or corneal infections by P. aeruginosa [30], extending the potent pro-inflammatory role of this pathogen to skin infections. IL-32 is a cytokine involved in the induction of IL-6, TNFα and chemokines [31,32].…”