Abstract:The masticatory system is a coordinated machine, highly adaptable to environmental demands. Increased levels of interleukin 6 (IL6) in the synovial fluid have been associated with temporomandibular disorders. Although they are mostly suggested released from inflammatory cells, it has been reported that IL6 is also a “myokine”, released by muscle cells during activity or in pathological processes. A pivotal role of IL6 in skeletal muscle and bone has been suggested, being related to both anabolic and catabolic … Show more
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