Interleukin-38 Level and Polymorphism (Rs 6743376) Associated with Rheumatoid Arthritis
Mohammed Issa Ibrahim Islemeh,
Bushra Mubarak,
Amina Elahi
Abstract:Rheumatoid arthritis (RA) is a multifaceted autoimmune disorder defined by persistent inflammation and joint damage. This study explores the intricate relationship between RA severity and interleukin-38 (IL-38), a cytokine having anti-inflammatory properties. Our research reveals a strong connection between elevated plasma IL-38 levels and the severity of RA, indicating IL-38's crucial role in modulating inflammation. Elevated ESR levels in RA patients highlight active inflammation. Genetic analysis shows spec… Show more
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