Interim analysis at 6 months from the LEG-flow Drug Eluting Balloon for the treatment of femoropopliteal occlusions (LEG-DEB) registry

Stabile, Eugenio; Magliulo, Fabio; Zhelev, D; Chervenkoff, V.; Taeymans, Kim; Goverde, Peter; Losi, Maria Angela; Giugliano, Giuseppe; Trimarco, Bruno; Esposito, Giovanni

doi:10.1016/j.ijcard.2016.08.146

Cited by 3 publications

(3 citation statements)

References 4 publications

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“…Femoropopliteal artery occlusion results in muscle ischemia in the calf (20,21), although it can be relieved by collateral circulation (22,23). Intermittent claudication frequently occurs in the cases with severe artery stenosis, as insufficiency of blood supply further deteriorates in exercise (24).…”

Section: Discussionmentioning

confidence: 99%

“…The most important findings were as follows: (i) the radiomics signature had a greater AUC than the mean CT density; and (ii) the radiomics signature is highly accurate in identifying muscle ischemia. Femoropopliteal artery occlusion results in muscle ischemia in the calf (20,21), although it can be relieved by collateral circulation (22,23). Intermittent claudication frequently occurs in the cases with severe artery stenosis, as insufficiency of blood supply further deteriorates in exercise (24).…”

Section: Discussionmentioning

confidence: 99%

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Radiomics of CTA is feasible in identifying muscle ischemia

Ling¹,

et al. 2022

Acta Radiol

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Background Advanced models based on computed tomography angiography (CTA) radiomics features in discriminating muscle ischemia from normal condition are lacking. Purpose To investigate the feasibility of radiomics of CTA in discriminating ischemic muscle from normal muscle. Material and Methods A total of 102 patients (51 ischemia and 51 non-ischemia) were analyzed using a CTA radiomics method. The radiomics features of muscle were compared between ischemic and normal cases. The maximum relevance minimum redundancy (mRMR) algorithm and least absolute shrinkage and selection operator (LASSO) logistic regression model were used. The receiver operating characteristic (ROC) curve was used to determine the performance of radiomics signature. Results Thirty-nine CTA radiomics features were significantly different between the two groups ( P < 0.05). By LASSO, six features were used to construct a model. The signature area under the curve was 0.92 and 0.91 in the training and validation cohorts, respectively. The sensitivity and specificity of the signature were 92% and 86% for the training cohort, and 80% and 94% for the validation cohort, respectively. Conclusion CTA radiomics signature is useful in identifying ischemic muscle in selected patients.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Radiomics of CTA is feasible in identifying muscle ischemia

Ling¹,

et al. 2022

Acta Radiol

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“…In the first case, before inserting the stent, a sphincterectomy is performed which allows direct access to the interior of the biliary ducts; in some cases, however, before inserting the stent the obstructed biliary duct is expanded by inflating a balloon in its interior. PTC, on the other hand, involves needle puncture of the biliary ducts through the skin at the level of the right hip or epigastric region, to provide access anatomical zones which are sites of movement, such as the common femoral artery and popliteal artery, in which the placement of a stent could be subject to frequent complications due to fracture of the stent itself [5,6]. Nevertheless, there are limitations to the use of DEB, such as the incapacity to treat flaps of dissecations, and a lower efficacy in the case of severely calcified arteries on account of the smaller quantity of antiproliferative drug absorbed by the arterial wall.…”

Section: Biliary Stentingmentioning

confidence: 99%

Evolution of surgical techniques for a progressive risk reduction

Amato

Santoro

Izzo

et al. 2017

Monaldi Arch Chest Dis

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Advanced age is a strong predictor of high perioperative mortality in surgical patients and patients aged 75 years and older have an elevated surgical risk, much higher than that of younger patients. Progressive advances in surgical techniques now make it possible to treat high-risk surgical patients with minimally invasive procedures. Endovascular techniques have revolutionized the treatment of several vascular diseases, in particular carotid stenosis, aortic pathologies, and severely incapacitating intermittent claudication or critical limb ischemia. The main advantages of the endovascular approach are the low complication rate, high rate of technical success and a good clinical outcome. Biliary stenting has improved the clinical status of severely ill patients with bile duct stricture before major surgery, and represents a good palliative therapy in the case of malignant biliary obstruction.

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