Dehumanization, the belief that other people are less than fully human, dampens empathy, increases animosity, and catalyzes conflict between groups. Research has revealed that a troubling number of American partisans blatantly dehumanize members of the other party. Nonetheless, this research has also found that partisans substantially overestimate the extent to which members of the rival party dehumanize them. Here, we predict that partisans’ perceptions of being dehumanized by rival partisans (or meta-dehumanization) leads them to respond with reciprocal dehumanization. By implication, partisans’ own dehumanization of rival partisans could be reduced by correcting their exaggerated meta-dehumanization. We test this hypothesis in a pre-registered, nationally-representative survey experiment of Democrats and Republicans (N = 2,127). We find that a brief, informational intervention correcting partisans’ exaggerated perceptions of how much rival partisans dehumanize them reduced levels of partisan dehumanization by 45%, and this effect persisted in a follow-up survey conducted approximately one week later. We also investigated the effects of our intervention on additional outcomes, finding that it reduced desire for social distance from, and negative affect toward, rival partisans, and that these effects also persisted a week later. Together, these results suggest that correcting inaccurate perceptions of the extent of partisan dehumanization can be a tool for durably mitigating partisan enmity.