Interfiber tension transmission in series‐fibered muscles of the cat hindlimb

Trotter, John A.

doi:10.1002/jmor.1052060312

Cited by 85 publications

(50 citation statements)

References 54 publications

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“…These two structures are a part of both the series and passive elements (Street & Ramsey, 1965;Trotter, 1990). However, data from the present study do not support either of these two structures as the site of materials fatigue.…”

Section: G L Warren Aind Otherscontrasting

confidence: 55%

Materials fatigue initiates eccentric contraction‐induced injury in rat soleus muscle.

Warren

Hayes

Lowe

et al. 1993

The Journal of Physiology

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SUMMARY1. The initiation of exercise-induced muscle injury is thought to be the result of high tensile stresses produced in the muscle during eccentric contractions. Materials science theory suggests that high tensile stresses could initiate the injury during the first eccentric contraction (normal stress theory) or after multiple eccentric contractions (materials fatigue). It was the objective of this study to investigate the two possibilities.2. Rat soleus muscles (n = 66; 11 protocols with 6 muscles per protocol) were isolated, placed in an oxygenated Krebs-Ringer buffer at 37°C, and baseline measurements were made. The muscle then performed an injury protocol which consisted of between zero and ten eccentric contractions (muscle starting length = 0 90 soleus muscle length, Lo; length change = 0-25 Lo; velocity =1V5 Lo/s; peak force = 180% maximal isometric tetanic tension (PO); time between contractions = 4 min; total duration of the injury protocol = 40 min). At the end of the injury protocol. the muscle was incubated in buffer for 1 h; every 15 min, an isometric twitch and tetanus were performed and lactate dehydrogenase (LDH) release was measured. Total muscle [Ca2"] was measured at the end of the incubation.3. Change-point regression analysis indicates that at 0 min into the incubation, declines in Po, maximal rate of tension development (+dP/dt), maximal rate of relaxation (-dP/dt), and muscle stiffness (dP/dx) became significantly greater after eight eccentric contractions (p < 0 05). No relation was found between the number of eccentric contractions performed and the LDH activity at 0 min into the incubation, although after 60 min of incubation, LDH activity in the buffer was linearly related to eccentric contraction number (p = 0 01). There was no relationship between total muscle [Ca2+] and eccentric contraction number. These findings support the materials fatigue hypothesis of exercise-induced muscle injury.

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Section: G L Warren Aind Otherscontrasting

confidence: 55%

Materials fatigue initiates eccentric contraction‐induced injury in rat soleus muscle.

Warren

Hayes

Lowe

et al. 1993

The Journal of Physiology

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“…Such muscle fibers end, in a variety of morphologies (e.g., Hijikata & Ishikawa, 1997;Hijikata et al, 1993;Huijing, 1999b), somewhere in the middle of the muscle belly. For non-spanning fibers, it has been argued (Trotter, 1990(Trotter, , 1991(Trotter, , 1993Trotter & Purslow, 1992;Hijikata et al, 1993;Trotter et al, 1995;Hijikata & Ishikawa, 1997), that shearing of intact endomysial -basal lamina -sarcolemma complexes of adjacent muscle fibers is determinant for intramuscular transmission of force from muscle fiber onto adjacent muscle fiber. In such a case, after transmission of force from a source fiber to target fiber, force could be transmitted further by serial transmission via sarcomeres onto the myotendinous junction of the target fiber.…”

Section: Effects Of Lower Limb Connective Tissue On Muscular Functionmentioning

confidence: 99%

“…Such a mechanism of force transmission has been shown to be active in experiments on single isolated muscle fibers (Ramsey & Street, 1940), small fascicles (Street, 1983;Street & Ramsey, 1965). Its activity has also been inferred in non-spanning fibered muscle (Trotter, 1990(Trotter, , 1991(Trotter, , 1993Trotter & Purslow, 1992;Trotter et al, 1995;. Non-spanning muscle fibers do not span the distance between proximal and distal muscle fiber attachment areas of a muscle on aponeuroses or bone, i.e., they end somewhere in a fascicle that is attached at both ends.…”

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confidence: 99%

Myofascial Force Transmission Causes Interaction between Adjacent Muscles and Connective Tissue: Effects of Blunt Dissection and Compartmental Fasciotomy on Length Force Characteristics of Rat Extensor Digitorum Longus Muscle

Huijing

Baan

2001

Archives of Physiology and Biochemistry

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Muscles within the anterior tibial compartment (extensor digitorum longus: EDL, tibialis anterior: TA, and extensor hallucis longus muscles: EHL) and within the peroneal compartment were excited simultaneously and maximally. The ankle joint was fixed kept at 90°. For EDL length force characteristics were determined. This was performed first with the anterior tibial compartment intact (1), and subsequently after: (2) blunt dissection of the anterior and lateral interface of EDL and TA. (3) Full longitudinal lateral fasciotomy of the anterior tibial compartment. (4) Full removal of TA and EHL muscles.Length-force characteristics were changed significantly by these interventions. Blunt dissection caused a force decrease of approximately 10% at all lengths, i.e., without changing EDL optimum or active slack lengths. This indicates that intermuscular connective tissue mediates significant interactions between adjacent muscles. Indications of its relatively stiff mechanical properties were found both in the physiological part of the present study, as well as the anatomical survey of connective tissue. Full lateral compartmental fasciotomy increased optimum length and decreased active slack length, leading to an increase of length range (by ഠ47%), while decreasing optimal force. As a consequence an increase in force for the lower length range was found. Such changes of length force characteristics are compatible with an increased distribution of fiber mean sarcomere length. On the basis of these results, it is concluded that extramuscular connective tissue has a sufficiently stiff connection to intramuscular connective tissue to be able to play a role in force transmission. Therefore, in addition to intramuscular myofascial force transmission, extramuscular force transmission has to be considered within intact compartments of limbs. A survey of connective tissue structures within the compartment indicated sheet-like neuro-vascular tracts to be major components of extramuscular connective tissue with connections to intramuscular connective tissue stroma.Removal of TA and EHL yielded yet another decrease of force (mean for optimal force ഠ10%). No significant changes of optimum and active slack lengths could be shown in this case. It is concluded that myofascial force transmission should be taken into account when considering muscular function and its coordination, and in clinical decisions regarding fasciotomy and repetitive strain injury. In order to obtain whole body movement, forces need to be transmitted from the muscles to the skeleton to cause acceleration of the limbs. A major location for force transmission is the well-studied myotendinous junction (e.g., Tidball, 1983Tidball, , 1984Tidball, , 1991Tidball, , 1994Tidball & Daniel, 1986;Tidball & Quan, 1992). Such transmission involving transmission of force from one sarcomere to its serial neighbors and eventually onto the myotendinous junction. These junctions are located at the apical ends of muscle fibers, where sarcomeric forces are transmitted onto an...

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“…muscle fibers that do not fully span the distance between the proximal and distal aponeuroses, but end within the muscle belly) has given another major push to the development of knowledge about mechanisms of force transmission by pathways other than myotendinous pathways (Loeb, 1984;Trotter, 1990;Hijikata et al, 1993;Trotter et al, 1995).…”

Section: Essentials Of Myofascial Force Transmissionmentioning

confidence: 99%

Adaptation of muscle size and myofascial force transmission: a review and some new experimental results

Huijing

Jaspers

2005

Scandinavian Med Sci Sports

126

106

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This paper considers the literature and some new experimental results important for adaptation of muscle fiber cross‐sectional area and serial sarcomere number. Two major points emerge: (1) general rules for the regulation of adaptation (for in vivo immobilization, low gravity conditions, synergist ablation, tenotomy and retinaculum trans‐section experiments) cannot be derived. As a consequence, paradoxes are reported in the literature. Some paradoxes are resolved by considering the interaction between different levels of organization (e.g. muscle geometrical effects), but others cannot. (2) An inventory of signal transduction pathways affecting rates of muscle protein synthesis and/or degradation reveals controversy concerning the pathways and their relative contributions. A major explanation for the above is not only the inherently limited control of the experimental conditions in vivo, but also of in situ experiments. Culturing of mature single Xenopus muscle fibers at high and low lengths (allowing longitudinal study of adaptation for periods up to 3 months) did not yield major changes in the fiber cross‐sectional area or the serial sarcomere number. This is very different from substantial effects (within days) of immobilization in vivo. It is concluded that overall strain does not uniquely regulate muscle fiber size. Force transmission, via pathways other than the myotendinous junctions, may contribute to the discrepancies reported: because of substantial serial heterogeneity of sarcomere lengths within muscle fibers creating local variations in the mechanical stimuli for adaptation. For the single muscle fiber, mechanical signalling is quite different from the in vivo or in vitro condition. Removal of tensile and shear effects of neighboring tissues (even of antagonistic muscle) modifies or removes mechanical stimuli for adaptation. It is concluded that the study of adaptation of muscle size requires an integrative approach taking into account fundamental mechanisms of adaptation, as well as effects of higher levels of organization. More attention should be paid to adaptation of connective tissues within and surrounding the muscle and their effects on muscular properties.

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Interfiber tension transmission in series‐fibered muscles of the cat hindlimb

Cited by 85 publications

References 54 publications

Materials fatigue initiates eccentric contraction‐induced injury in rat soleus muscle.

Materials fatigue initiates eccentric contraction‐induced injury in rat soleus muscle.

Myofascial Force Transmission Causes Interaction between Adjacent Muscles and Connective Tissue: Effects of Blunt Dissection and Compartmental Fasciotomy on Length Force Characteristics of Rat Extensor Digitorum Longus Muscle

Adaptation of muscle size and myofascial force transmission: a review and some new experimental results

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