“…In case of coronavirus infection, either MERS-CoV or SARSCoV, it was observed that virus infection induces an excessive activation of the immune system which leads to the synthesis of several pro-inflammatory cytokines like interleukin-1beta (IL-1B), IL-6, IL-8, CXC-chemokine ligand 10 (CXCL10), CC-chemokine ligand 2 (CCL2), and interferon-γ (IFN-γ) [9][10][11][12]. This proinflammatory response will ultimately induce pulmonary circulation capillary leakage which will lead to non-cardiogenic pulmonary edema, hypoxemia, type II pneumocyte hyperplasia, and neutrophil infiltration.…”