Interferon alfa-2b–induced Meyerson’s nevi in a patient with dysplastic nevus syndrome

Krischer, Joachim; Péchère, M.; Salomon, Denis; Harms, Monika; Chavaz, P.; Saurat, Jean‐Hilaire

doi:10.1016/s0190-9622(99)70538-4

Cited by 33 publications

(20 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…11 Meyerson phenomenon has been attributed to ultraviolet radiation in a case of Meyerson and halo naevi occurring after severe sunburn. 5 Multiple Meyerson naevi developed in a patient with Behcet's disease treated with interferon-alpha 12 and there is a well documented association of Meyerson phenomenon and combination therapy of interferon-alpha with riboflavin for the treatment of hepatitis C virus. 13 Interferon is thought to up-regulate intercellular adhesion molecule expression on keratinocytes and dermal endothelial cells.…”

Section: Discussionmentioning

confidence: 99%

Early melanoma with halo eczema (Meyerson's phenomenon)

Rodins¹,

Byrom²,

Muir³

2010

Australasian Journal of Dermatology

View full text Add to dashboard Cite

We present a case of a 49-year-old man who presented with a solitary atypical pigmented lesion with a surrounding halo of dermatitis. Dermoscopy showed a pigment network at the periphery with areas of scar-like depigmentation, negative pigment network and erythema. The lesion was treated preoperatively with a potent topical corticosteroid resulting in a reduction of inflammation. Histology showed an early Clark level 1 melanoma arising within a severely dysplastic compound melanocytic naevus. There was an adjacent perivascular chronic inflammatory cell infiltrate with occasional eosinophils. Minimal, though definite spongiosis with parakeratosis was also present. The scar was subsequently re-excised achieving appropriate excision margins for melanoma in situ. Six months later, there was recurrence of dermatitis at the scar with no evidence of recurrent melanoma. To our knowledge, melanoma with Meyerson phenomenon has not been reported in the literature. This case highlights that all lesions should be evaluated on clinical and dermoscopic grounds regardless of the presence or absence of eczema. Our case adds yet another entity that may display Meyerson phenomenon and consequently a halo of eczema cannot be considered a reassuring sign when evaluating melanocytic lesions.

show abstract

Section: Discussionmentioning

confidence: 99%

Early melanoma with halo eczema (Meyerson's phenomenon)

Rodins¹,

Byrom²,

Muir³

2010

Australasian Journal of Dermatology

View full text Add to dashboard Cite

show abstract

“…Since then, the ‘Meyerson phenomenon’ [6], also called ‘nevocentric’ halo dermatitis [13], has rarely been seen in relation with other skin tumors [7, 8]or inflammatory skin diseases such as atopic eczema (own observation), pityriasis rosea [14], erythema multiforme [13]and psoriasis [15]. Even if an immunological process is suggested [16, 17, 18], the exact pathogenesis of this phenomenon has yet to be clarified.…”

Section: Discussionmentioning

confidence: 99%

Meyerson Phenomenon within a Nevus flammeus

Hofer¹

2002

Dermatology

View full text Add to dashboard Cite

Only few reports about eczematous reactions overlying nevi flammei exist. All of them were observed in children. The description of an eczematous reaction within a congenital nevus flammeus on the left lower leg of a male adult gives reason to discuss this rare phenomenon. Eczema or inflammatory changes within a port-wine stain may mostly be a collision dermatosis with an atopic dermatitis, especially when they arise in children and are localized to the neck and face. When they are observed within a grossly visible vascular malformation, as for example in the Klippel-Trenaunay syndrome, they may have a pathogenesis similar to stasis dermatitis. In rare cases, an eczematous reaction within a nevus flammeus may be the result of genetic mosaicism and is interpreted as a variant of the so-called Meyerson phenomenon.

show abstract

“…15 Triggering factors, such as ultraviolet radiation, 8 chemotherapy, or alpha-2B-interferon, have been suggested. 19 Even if a triggering antigen exists, it has not been yet identified.…”

Section: Clinical Presentationmentioning

confidence: 99%

Eponyms, Morphology, and Pathogenesis of Some Less Mentioned Types of Melanocytic Nevi

Fernández-Flores

2012

The American Journal of Dermatopathology

View full text Add to dashboard Cite

Some types of melanocytic nevi are seldom mentioned in the literature and are therefore less well known. In the current study, we focus on the concepts of eponyms, synonyms, clinical presentation, and morphology of the following types: Meyerson nevus, cockarde (or cockade) nevus, Hori nevus, Sun nevus, Hidanos nevus, Duperrat nevus, Spark nevus, nevus spilus, eclipse nevus, Kerl nevus, and Kopf nevus.

show abstract

Interferon alfa-2b–induced Meyerson’s nevi in a patient with dysplastic nevus syndrome

Cited by 33 publications

References 3 publications

Early melanoma with halo eczema (Meyerson's phenomenon)

Early melanoma with halo eczema (Meyerson's phenomenon)

Meyerson Phenomenon within a Nevus flammeus

Eponyms, Morphology, and Pathogenesis of Some Less Mentioned Types of Melanocytic Nevi

Contact Info

Product

Resources

About