Interference of α-hemolytic streptococci isolated from tonsillar surface on β-hemolytic streptococci (Streptococcus pyogenes) — A methodological study

Grahn, Eva; Holm, Stig E.; Ekedahl, C; Roos, Kristian

doi:10.1016/s0174-3031(83)80129-2

Cited by 27 publications

(31 citation statements)

References 15 publications

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“…The ability of the indigenous normal nasopharyngeal flora to inhibit colonization with potential pathogens has been studied in several URTI [15][16][17][18][19]. Alpha-hemolytic streptococci were found to inhibit the colonization in patients and in vitro growth of a variety of pathogenic bacteria.…”

Section: Introductionmentioning

confidence: 99%

Effects of exposure to smoking on the microbial flora of children and their parents

Brook

2010

International Journal of Pediatric Otorhinolaryngology

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Section: Introductionmentioning

confidence: 99%

Effects of exposure to smoking on the microbial flora of children and their parents

Brook

2010

International Journal of Pediatric Otorhinolaryngology

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“…An additional untoward effect of penicillins therapy is the potential eradication, in the absence of BLPB, of AHS that possess inhibiting activity of GABHS [3,11]. These AHS may have a beneficial role by competing with GABHS, and preventing colonization and subsequent infection with GABHS.…”

Section: Discussionmentioning

confidence: 99%

“…These AHS may have a beneficial role by competing with GABHS, and preventing colonization and subsequent infection with GABHS. However, since these organisms are generally as susceptible to penicillins as is GABHS, they can also be eradicated by penicillin therapy [11]. In contrast, AHS are usually more resistant to cephalosporins [8,11].…”

Section: Discussionmentioning

confidence: 99%

“…However, since these organisms are generally as susceptible to penicillins as is GABHS, they can also be eradicated by penicillin therapy [11]. In contrast, AHS are usually more resistant to cephalosporins [8,11]. This difference in susceptibility and the resistance of cephalosporins to b-lactamase produced by S. aureus and other aerobic bacteria may explain their improved activity as compared with penicillin in the treatment of acute GABHS PT [5].…”

Section: Discussionmentioning

confidence: 99%

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Rate of eradication of group A beta-hemolytic streptococci in children with pharyngo-tonsillitis by amoxicillin and cefdinir

Brook

Gober

2009

International Journal of Pediatric Otorhinolaryngology

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“…Sanders et al [13] and later Grahn et al [14] showed that some alpha-streptococci may have an inhibiting capacity on group A streptococci in vitro. Anaerobes such as peptostreptococci and Prevotella [15••] have also been suggested to function in preventing overgrowth and invasion of potential pathogens.…”

Section: Bacterial Interferencementioning

confidence: 99%

The use of probiotics in head and neck infections

Roos

Holm²

2002

Curr Infect Dis Rep

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Recurrent episodes of infections in the upper respiratory tract are very common. The pathogenesis behind these recurrences is still not well understood, but much attention has been paid to the adherence of the microorganisms to epithelial structures and to the protective function of the normal bacterial flora (bacterial interference). Thus, in vitro as well as in vivo studies have shown that both aerobic and anaerobic bacteria of the normal flora in the upper respiratory tract can hinder the growth of pathogens and the establishment of a renewed infection. Studies have shown that lack of interfering bacteria facilitates recurrence of these diseases. Recolonization with interfering alpha-streptococci has been performed successfully in acute streptococcal pharyngotonsillitis, as well as in acute otitis media. The number of recurrences has significantly been lowered in these diseases after recolonization with alpha-streptococci, which is the dominating normal bacteria in the upper respiratory tract. Several mechanisms have been proposed to be responsible for this interaction, such as competition of the adhering sites at the epithelial cells, production of hydrogen peroxide, competition for nutritients, and production of specific growth inhibiting factors such as bacteriocins. Other human components like lactoferrin are also important in the defense against microorganisms, and are important parts of the unspecific and specific immune system.

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Interference of α-hemolytic streptococci isolated from tonsillar surface on β-hemolytic streptococci (Streptococcus pyogenes) — A methodological study

Cited by 27 publications

References 15 publications

Effects of exposure to smoking on the microbial flora of children and their parents

Effects of exposure to smoking on the microbial flora of children and their parents

Rate of eradication of group A beta-hemolytic streptococci in children with pharyngo-tonsillitis by amoxicillin and cefdinir

The use of probiotics in head and neck infections

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