Interference of medicines in laboratory exams

Abstract

The history of muscle biopsy dates back to 1860, when Duchenne first performed a biopsy on a patient with symptoms of myopathy (1) . Since then, the basic and clinical science of muscle and muscle disease has gone through three stages of development: the classical period, the modern stage and the molecular era.

Drug interference with biochemical laboratory tests

“…All these factors significantly contribute to complex and careful drug therapy in the elderly and need for improved knowledge about DLTIs ( 23 ). Medical professionals should be educated that it is essential to obtain patient data about medications as well as the timing of drug used by the patient within 10 days before collecting biological material for the correct conduction and interpretation of a laboratory test ( 24 ).…”

Analysis of drug interactions and their implications for laboratory test results

“…Several categories of drugs, according to Silva et al (9), have the potential to interfere with the results of laboratory tests, such as drugs that impact liver function assessment tests, such as hepatotoxic drugs, capable of promoting the performance of liver enzymes, such as alanine aminotransferase (ALT ) and aspartate aminotransferase (AST), generating false positive results for liver damage.…”

“…Health professionals play a significant role in providing guidance to patients about the importance of adhering to the instructions for using antibiotics, respecting the recommended doses and times, in order to ensure the effectiveness of the treatment (9,13). Yeah, they are medicines used to fight bacterial infections; however, it is crucial to avoid the indiscriminate use of these drugs, which can lead to the development of bacterial resistance.…”

“…Patient awareness of the possible effects of beta-blockers on laboratory tests is essential. Following medical guidelines and fully and accurately informing the use of these drugs is crucial to obtain accurate laboratory results, thus ensuring the safety and efficacy of the treatment (9). The table below (Table 5) presents drug information about betablockers.…”

“…These drugs work in different ways, such as blocking angiotensin receptors, inhibiting angiotensinconverting enzyme, and decreasing peripheral vascular resistance. These actions promote blood vessel dilation and reduce the heart's workload, resulting in effective blood pressure control (9). It is essential to emphasize that the correct use of antihypertensive drugs is crucial for the success of the treatment.…”