Interfaces in Multiphase Polymers and Nanomedicines

Abstract

Crystalline and amorphous interfaces were formed and modified in multiphase composite and pharmaceutical systems. Nanosize drug of antacid effect was prepared in continuous extrusion process. The structural features were analyzed using (micro-) thermal analytical and (micro-) Raman spectrometric methods combined with chemometric evaluation.

Solvent-Free Melt Electrospinning for Preparation of Fast Dissolving Drug Delivery System and Comparison with Solvent-Based Electrospun and Melt Extruded Systems

“…Solid micro‐ and nanodispersions, or even solid solution, are some of the most promising strategies to improve drug dissolution 10–15. The potential of solvent‐free melt extrusion (EX) to increase the drug dissolution rate has been demonstrated by numerous papers,16–22 and marketed products prepared by this method (e.g. Kaletra® and Isoptin‐SRE® (Abbott, Chicago, Illinois)) 23.…”