Intérêt de la tomographie par émission de positons au ( 18 F)-fluorodésoxyglucose pour la planification de la radiothérapie des cancers de l’œsophage localement évolués ou inopérables

PET imaging in adaptive radiotherapy of gastrointestinal tumors

“…In comparison to a CT-based GTV delineation, focussing on the radial extent of the tumour, Vali et al 20 found that the use of an SUV threshold of 2.5 had the best performance of 11 different SUV-based approaches for [ 18 F]FDG-PET/CT-based delineation of the MTV in 22 patients with oesophageal cancer. In contrast, the signal-to-background ratio (SBR) was the most optimal automatic segmentation method found in a retrospective study of Encaoua et al 21 in 58 patients. The CT-based GTV was significantly longer than the GTV based on SBR, resulting in lower doses to the lungs, heart, and spinal cord when radiotherapy plans were based on the SBR-based PTV.…”