“…Despite rapid progress in organocatalytic asymmetric cascade reactions with α-isothiocyanato compounds as reagents has been made, the types of chemical reaction in this area are still limited in number. Accordingly, it might be one promising and exciting research field to develop novel asymmetric cascade reactions between the α-isothiocyanato compounds and other accepters, such as nitrosoarenes [46], N-sulfinylanilines [47], oxaziridines [48], nitrones [49], azomethine imines [50], α-halo N-acyl hydrazones [51], epoxidation [52], et al Moreover, making further insight into the reaction mechanism concerning α-isothiocyanato reagents will facilitate the rapid development of the new methodology in this realm. In summary, the research by employing α-isothiocyanato compounds for the construction of complex heterocyclic compounds via organocatalytic asymmetric cascade process has broad development space.…”